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Submit Reviewβ-Pompilidotoxin
Discontinued Product
β-Pompilidotoxin (Cat. No. 1539) has been withdrawn from sale for commercial reasons.
Description: Slows neuronal Na+ channel inactivation
Alternative Names: β-PMTX
Biological Activity for β-Pompilidotoxin
β-Pompilidotoxin is a novel wasp neurotoxin that slows Na+ channel inactivation. Facilitates neuromuscular synaptic transmission and discriminates between rat neuronal and cardiac Na+ channel α-subunits.
Licensing Information
Sold with the permission of Suntory Ltd.
Technical Data for β-Pompilidotoxin
| M. Wt | 1557.9 |
| Formula | C71H124N22O17 |
| Sequence |
RIKIGLFDQLSRL (Modifications: Leu-13 = C-terminal amide) |
| Storage | Desiccate at -20°C |
| CAS Number | 216064-36-7 |
| PubChem ID | 90479801 |
| InChI Key | YBOJYGJMKPMNRC-QRIWDNSUSA-N |
| Smiles | [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for β-Pompilidotoxin
References for β-Pompilidotoxin
References are publications that support the biological activity of the product.
Kinoshita et al (2001) Novel wasp toxin discriminates between neuronal and cardiac sodium channels. Mol.Pharmacol. 59 1457 PMID: 11353806
Konno et al (1998) Isolation and structure of pompilidotoxins, novel peptide neurotoxins in solitary wasp venoms. Biochem.Biophys.Res.Commun. 250 612 PMID: 9784394
Miyawaki et al (2002) Differential effects of novel wasp toxin on rat hippocampal interneurons. Neurosci.Lett. 328 25 PMID: 12123851
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Keywords: beta-Pompilidotoxin, beta-Pompilidotoxin supplier, Slows, neuronal, Na+, channels, inactivation, Sodium, NaV, voltage-gated, voltage-dependent, beta-Pompilidotoxin, β-PMTX, beta-PMTX, neurotoxins, venoms, b-PMTX, Voltage-gated, Channels, 1539, Tocris Bioscience
Citations for β-Pompilidotoxin
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Currently there are no citations for β-Pompilidotoxin.
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