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Biological Activity for ASP 9521
ASP 9521 is a potent 17β-hydroxysteroid dehydrogenase type 5 inhibitor (IC50 = 11 - 49 nM). Suppresses androstenedione-dependent protein-specific antigen (PSA) production and cell proliferation in LNCaP cells in vitro. Orally bioavailable.
Technical Data for ASP 9521
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References for ASP 9521
References are publications that support the biological activity of the product.
Kikuchi et al (2014) In vitro and in vivo characterisation of ASP9521: a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17βHSD5; AKR1C3). Invest.New Drugs 32 860 PMID: 24981575
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Keywords: ASP 9521, ASP 9521 supplier, ASP9521, 17beta, 17B, hydroxysteroid, dehydrogenase, type, 5, inhibitors, inhibits, 17β-HSD5, AK1RC3, potent, orally, bioavailable, Other, Dehydrogenases, 6084, Tocris Bioscience
Citations for ASP 9521
Citations are publications that use Tocris products.
Currently there are no citations for ASP 9521.
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