Arecaidine propargyl ester tosylate
A potent muscarinic receptor agonist. Shows some selectivity for cardiac versus ileal M2 receptors.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 100 mM in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 351.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.85 mL||14.23 mL||28.46 mL|
|5 mM||0.57 mL||2.85 mL||5.69 mL|
|10 mM||0.28 mL||1.42 mL||2.85 mL|
|50 mM||0.06 mL||0.28 mL||0.57 mL|
References are publications that support the products' biological activity.
Barlow and Weston-Smith (1985) The relative potencies of some agonists at M2 muscarinic receptors in guinea pig ileum, atria and bronchi. Br.J.Pharmacol. 85 437 PMID: 3896364
Moser et al (1989) Structure-activity relationships of new analogues of arecaidine propargyl ester at muscarinic M1 and M2 receptor subtypes. Br.J.Pharmacol. 96 319 PMID: 2924082
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Keywords: Arecaidine propargyl ester tosylate, supplier, Muscarinic, agonists, Receptors, Acetylcholine, Ach, M2, Receptors, M2, Receptors, Tocris Bioscience
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