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Submit ReviewArecaidine propargyl ester tosylate is an a potent muscarinic receptor agonist. Shows some selectivity for cardiac versus ileal M2 receptors.
M. Wt | 351.42 |
Formula | C10H13NO2.C7H8SO3 |
Storage | Store at RT |
CAS Number | 147202-94-6 |
PubChem ID | 6604936 |
InChI Key | LYHWIOMAWPVTPI-UHFFFAOYSA-N |
Smiles | CC1=CC=C(C=C1)S(O)(=O)=O.CN1CCC=C(C1)C(=O)OCC#C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
water | 100 |
The following data is based on the product molecular weight 351.42. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 2.85 mL | 14.23 mL | 28.46 mL |
5 mM | 0.57 mL | 2.85 mL | 5.69 mL |
10 mM | 0.28 mL | 1.42 mL | 2.85 mL |
50 mM | 0.06 mL | 0.28 mL | 0.57 mL |
References are publications that support the biological activity of the product.
Barlow and Weston-Smith (1985) The relative potencies of some agonists at M2 muscarinic receptors in guinea pig ileum, atria and bronchi. Br.J.Pharmacol. 85 437 PMID: 3896364
Moser et al (1989) Structure-activity relationships of new analogues of arecaidine propargyl ester at muscarinic M1 and M2 receptor subtypes. Br.J.Pharmacol. 96 319 PMID: 2924082
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Keywords: Arecaidine propargyl ester tosylate, Arecaidine propargyl ester tosylate supplier, Muscarinic, agonists, Receptors, Acetylcholine, Ach, M2, 0383, Tocris Bioscience
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Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.