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Submit ReviewArecaidine propargyl ester tosylate
Description: Muscarinic agonist
Chemical Name: N-Methyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid propargyl ester tosylate
Biological Activity for Arecaidine propargyl ester tosylate
Arecaidine propargyl ester tosylate is an a potent muscarinic receptor agonist. Shows some selectivity for cardiac versus ileal M2 receptors.
Technical Data for Arecaidine propargyl ester tosylate
| M. Wt | 351.42 |
| Formula | C10H13NO2.C7H8SO3 |
| Storage | Store at RT |
| CAS Number | 147202-94-6 |
| PubChem ID | 6604936 |
| InChI Key | LYHWIOMAWPVTPI-UHFFFAOYSA-N |
| Smiles | CC1=CC=C(C=C1)S(O)(=O)=O.CN1CCC=C(C1)C(=O)OCC#C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Arecaidine propargyl ester tosylate
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 100 |
Preparing Stock Solutions for Arecaidine propargyl ester tosylate
The following data is based on the product molecular weight 351.42. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.85 mL | 14.23 mL | 28.46 mL |
| 5 mM | 0.57 mL | 2.85 mL | 5.69 mL |
| 10 mM | 0.28 mL | 1.42 mL | 2.85 mL |
| 50 mM | 0.06 mL | 0.28 mL | 0.57 mL |
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Product Datasheets for Arecaidine propargyl ester tosylate
References for Arecaidine propargyl ester tosylate
References are publications that support the biological activity of the product.
Barlow and Weston-Smith (1985) The relative potencies of some agonists at M2 muscarinic receptors in guinea pig ileum, atria and bronchi. Br.J.Pharmacol. 85 437 PMID: 3896364
Moser et al (1989) Structure-activity relationships of new analogues of arecaidine propargyl ester at muscarinic M1 and M2 receptor subtypes. Br.J.Pharmacol. 96 319 PMID: 2924082
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Keywords: Arecaidine propargyl ester tosylate, Arecaidine propargyl ester tosylate supplier, Muscarinic, agonists, Receptors, Acetylcholine, Ach, M2, 0383, Tocris Bioscience
Citations for Arecaidine propargyl ester tosylate
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