Arecaidine propargyl ester tosylate

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Cat.No. 0383 - Arecaidine propargyl ester tosylate | C10H13NO2.C7H8SO3 | CAS No. 147202-94-6
Description: Muscarinic agonist
Chemical Name: N-Methyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid propargyl ester tosylate
Datasheet
Citations
Literature

Biological Activity

A potent muscarinic receptor agonist. Shows some selectivity for cardiac versus ileal M2 receptors.

Technical Data

M. Wt 351.42
Formula C10H13NO2.C7H8SO3
Storage Store at RT
CAS Number 147202-94-6
PubChem ID 6604936
InChI Key LYHWIOMAWPVTPI-UHFFFAOYSA-N
Smiles CC1=CC=C(C=C1)S(O)(=O)=O.CN1CCC=C(C1)C(=O)OCC#C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 351.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.85 mL 14.23 mL 28.46 mL
5 mM 0.57 mL 2.85 mL 5.69 mL
10 mM 0.28 mL 1.42 mL 2.85 mL
50 mM 0.06 mL 0.28 mL 0.57 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Barlow and Weston-Smith (1985) The relative potencies of some agonists at M2 muscarinic receptors in guinea pig ileum, atria and bronchi. Br.J.Pharmacol. 85 437 PMID: 3896364

Moser et al (1989) Structure-activity relationships of new analogues of arecaidine propargyl ester at muscarinic M1 and M2 receptor subtypes. Br.J.Pharmacol. 96 319 PMID: 2924082


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Keywords: Arecaidine propargyl ester tosylate, supplier, Muscarinic, agonists, Receptors, Acetylcholine, Ach, M2, Receptors, Tocris Bioscience

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