Arecaidine propargyl ester tosylate

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Description: Muscarinic agonist
Chemical Name: N-Methyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid propargyl ester tosylate
Literature (1)

Biological Activity for Arecaidine propargyl ester tosylate

Arecaidine propargyl ester tosylate is an a potent muscarinic receptor agonist. Shows some selectivity for cardiac versus ileal M2 receptors.

Technical Data for Arecaidine propargyl ester tosylate

M. Wt 351.42
Formula C10H13NO2.C7H8SO3
Storage Store at RT
CAS Number 147202-94-6
PubChem ID 6604936
Smiles CC1=CC=C(C=C1)S(O)(=O)=O.CN1CCC=C(C1)C(=O)OCC#C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Arecaidine propargyl ester tosylate

Solvent Max Conc. mg/mL Max Conc. mM
water 100

Preparing Stock Solutions for Arecaidine propargyl ester tosylate

The following data is based on the product molecular weight 351.42. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.85 mL 14.23 mL 28.46 mL
5 mM 0.57 mL 2.85 mL 5.69 mL
10 mM 0.28 mL 1.42 mL 2.85 mL
50 mM 0.06 mL 0.28 mL 0.57 mL

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Product Datasheets for Arecaidine propargyl ester tosylate

References for Arecaidine propargyl ester tosylate

References are publications that support the biological activity of the product.

Barlow and Weston-Smith (1985) The relative potencies of some agonists at M2 muscarinic receptors in guinea pig ileum, atria and bronchi. Br.J.Pharmacol. 85 437 PMID: 3896364

Moser et al (1989) Structure-activity relationships of new analogues of arecaidine propargyl ester at muscarinic M1 and M2 receptor subtypes. Br.J.Pharmacol. 96 319 PMID: 2924082

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Keywords: Arecaidine propargyl ester tosylate, Arecaidine propargyl ester tosylate supplier, Muscarinic, agonists, Receptors, Acetylcholine, Ach, M2, 0383, Tocris Bioscience

Citations for Arecaidine propargyl ester tosylate

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