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Submit ReviewAnti-mGlu5 blocking peptide
Discontinued Product
2102 has been discontinued.
View all Glutamate (Metabotropic) Group I Receptors products.
Description: Blocking peptide for anti-mGlu5 (Cat. No. 2032)
Biological Activity for Anti-mGlu5 blocking peptide
Synthetic peptide ([K]-SSPKYDTLIIRDYTQSSSSL) corresponding to the C-terminal amino acids 1184-1203 of rat precursor mGlu5 (Accession No. P31424) with a lysine added at the N-terminus of the peptide for conjugation. Immunogen used for anti-mGlu5 (Cat. No. 2032).
Technical Data for Anti-mGlu5 blocking peptide
| M. Wt | 2389.64 |
| Formula | C104H169N27O37 |
| Sequence | KSSPKYDTLIIRDYTQSSSSL |
| Storage | Desiccate at -20°C |
| Smiles | [H]N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Anti-mGlu5 blocking peptide
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References for Anti-mGlu5 blocking peptide
References are publications that support the biological activity of the product.
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Keywords: Anti-mGlu5 blocking peptide, Anti-mGlu5 blocking peptide supplier, Blocking, peptides, anti-mGlu5, mGluR5, Group, I, Receptors, Glutamate, Metabotropic, immunogen, (Metabotropic), 2102, Tocris Bioscience
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Metabotropic Glutamate Receptors Scientific Review
Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.
Addiction Poster
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Huntington's Disease Poster
Huntington's disease (HD) is a severe monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the effects of mutant huntingtin aggregation implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.
Parkinson's Disease Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.