You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Potent type III phosphodiesterase (PDE3) inhibitor (IC50 = 36 nM). Inhibits platelet aggregation and produces potent thrombocytopenic effects via inhibition of megakaryocyte maturation.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 292.55. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||34.18 mL||170.91 mL||341.82 mL|
|0.5 mM||6.84 mL||34.18 mL||68.36 mL|
|1 mM||3.42 mL||17.09 mL||34.18 mL|
|5 mM||0.68 mL||3.42 mL||6.84 mL|
References are publications that support the biological activity of the product.
Gillespie (1988) Anagrelide: a potent and selective inhibitor of platelet cyclic AMP phosphodiesterase enzyme activity. Biochem.Pharmacol. 37 2866 PMID: 2456068
Mazur et al (1992) Analysis of the mechanism of anagrelide-induced thrombocytopenia in humans. Blood 79 1931 PMID: 1562721
Wang et al (2005) Comparison of the biological activities of anagr. and its major metabolites in haematopoietic cell cultures. Br.J.Pharmacol. 146 324 PMID: 16041400
If you know of a relevant reference for Anagrelide hydrochloride, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Anagrelide hydrochloride, Anagrelide hydrochloride supplier, Potent, PDE3, inhibitors, inhibits, Phosphodiesterases, BL4162A, BL, 4162A, 2432, Tocris Bioscience
Citations for Anagrelide hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for Anagrelide hydrochloride. Do you know of a great paper that uses Anagrelide hydrochloride from Tocris? Please let us know.
Reviews for Anagrelide hydrochloride
There are currently no reviews for this product. Be the first to review Anagrelide hydrochloride and earn rewards!
Have you used Anagrelide hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.