Aminoguanidine hydrochloride

Pricing Availability   Qty
Cat.No. 0787 - Aminoguanidine hydrochloride | CH6N4.HCl | CAS No. 1937-19-5
Description: Irreversible iNOS inhibitor
Datasheet
Citations (1)
Reviews
Literature (3)

Biological Activity

Irreversible inhibitor of iNOS that displays some selectivity over eNOS and nNOS. Exhibits antioxidant and radioprotective effects in vivo.

Technical Data

M. Wt 110.55
Formula CH6N4.HCl
Storage Store at RT
CAS Number 1937-19-5
PubChem ID 16017
InChI Key UBDZFAGVPPMTIT-UHFFFAOYSA-N
Smiles Cl.N=C(NN)N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 100

Preparing Stock Solutions

The following data is based on the product molecular weight 110.55. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 9.05 mL 45.23 mL 90.46 mL
5 mM 1.81 mL 9.05 mL 18.09 mL
10 mM 0.9 mL 4.52 mL 9.05 mL
50 mM 0.18 mL 0.9 mL 1.81 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

References

References are publications that support the biological activity of the product.

Griffiths et al (1993) Aminoguanidine selectively inhibits inducible nitric oxide synthase. Br.J.Pharmacol. 110 963 PMID: 7507781

Huang et al (2009) Aminoguanidine alleviates radiation-induced small-bowel damage through its antioxidant effect. Int.J.Radiat.Oncol.Biol.Phys. 74 237 PMID: 19362242

Laszlo et al (1995) Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo. Eur.J.Pharmacol. 272 169 PMID: 7536162

Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 18 204 PMID: 9226999


If you know of a relevant reference for Aminoguanidine hydrochloride, please let us know.

View Related Products by Target

View Related Products by Product Action

View all iNOS Inhibitors

Keywords: Aminoguanidine hydrochloride, Aminoguanidine hydrochloride supplier, Irreversible, iNOS, inhibitors, inhibits, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, 0787, Tocris Bioscience

1 Citation for Aminoguanidine hydrochloride

Citations are publications that use Tocris products. Selected citations for Aminoguanidine hydrochloride include:

Jakubowska et al (2016) Nitric oxide signals are interlinked with calcium signals in normal pancreatic stellate cells upon oxidative stress and inflammation. Open Biol. 6 160149 PMID: 27488376


Do you know of a great paper that uses Aminoguanidine hydrochloride from Tocris? Please let us know.

Reviews for Aminoguanidine hydrochloride

There are currently no reviews for this product. Be the first to review Aminoguanidine hydrochloride and earn rewards!

Have you used Aminoguanidine hydrochloride?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Immunology

Immunology Product Listing

A collection of over 190 products for immunology research, the guide includes research tools for the study of:

  • Chemokine and Cytokine Signaling
  • Chemotaxis
  • Complement System
  • Immune Cell Signaling
  • Inflammation
Pain

Pain Research Product Guide

A collection of over 280 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling