[Ala113]-MBP (104-118)

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Cat.No. 1901 - [Ala113]-MBP (104-118) | Gly-Lys-Gly-Arg-Gly-Leu-Ser-Leu-Ser-Ala-Phe-Ser-Trp-Gly-Ala | CAS No. 99026-78-5
Description: Protein kinase C inhibitor
Alternative Names: [Ala113]-Myelin Basic Protein (104-118)
Datasheet
Citations
Reviews
Literature

Biological Activity

Synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 28 - 62 mM).

Technical Data

M. Wt 1493.68
Formula C67H104N20O19
Sequence GKGRGLSLSAFSWGA
Storage Desiccate at -20°C
CAS Number 99026-78-5
PubChem ID 71312078
InChI Key FBVMKAAYUXGGSU-NBRSAOMZSA-N
Smiles [H]NCC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)NCC(=O)N[C@@H](C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 2 mg/ml in 0.25% acetic acid

References

References are publications that support the biological activity of the product.

Su et al (1986) Synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase C). Biochem.Biophys.Res.Commun. 134 78 PMID: 2418828

Turner et al (1985) Substrate specificity of phospholipid/Ca2+ dependent protein kinase as probed with synthetic peptide fragments of the bovine myelin basic protein. J.Biol.Chem. 260 11503 PMID: 2413012


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Keywords: [Ala113]-MBP (104-118), [Ala113]-MBP (104-118) supplier, Protein, kinase, C, inhibitors, inhibits, PKC, Kinases, [Ala113]-MBP104-118, [Ala113]-Myelin, Basic, (104-118), Kinase, 1901, Tocris Bioscience

Citations for [Ala113]-MBP (104-118)

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