GABA receptor agonist and modulator of glutamatergic systems. Reduces alcohol consumption in animal models of alcohol addiction.
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|DMSO||2||10mM with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 200.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.99 mL||24.97 mL||49.94 mL|
|5 mM||1 mL||4.99 mL||9.99 mL|
|10 mM||0.5 mL||2.5 mL||4.99 mL|
|50 mM||0.1 mL||0.5 mL||1 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Spanagel et al (1996) Acamprosate and alcohol: I. Effects on alcohol intake following alcohol deprivation in the rat. Eur.J.Pharmacol. 305 39 PMID: 8813529
Berton et al (1998) Acamprosate enhances N-methyl-D-aspartate receptor-mediated neurotransmission but inhibits presynaptic GABA(B) receptors in nucleus accumbens neurons. Alcohol Clin.Exp.Res. 22 183 PMID: 9514305
Popp and Lovinger (2000) Interaction of acamprosate with ethanol and spermine on NMDA receptors in primary cultured neurons. Eur.J.Pharmacol. 394 221 PMID: 10771287
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Keywords: GABA agonists receptors glutamate modulators metabotropic mGlu mGluR ionotropic systems glutamatergics Calcium acetylhomotaurinate GABAA Receptors
Citations for Acamprosate calcium
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Literature in this Area
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