Discontinued ProductUnfortunately Ac-YVAD-AFC (Cat. No. 1572) has been withdrawn from sale for commercial reasons.
Fluorogenic peptide substrate for caspase-1 (ICE).
(Modifications: Tyr-1 = N-Ac-Tyr, Asp-4 = Asp-(7-amino-4-trifluoromethylcoumarin))
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 719.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.39 mL||6.95 mL||13.9 mL|
|5 mM||0.28 mL||1.39 mL||2.78 mL|
|10 mM||0.14 mL||0.69 mL||1.39 mL|
|50 mM||0.03 mL||0.14 mL||0.28 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Jones et al (1998) Fas-mediated apoptosis in mouse hepatocytes involves the processing and activation of caspases. Hepatology 27 1632 PMID: 9620337
Marks et al (1998) Activation of caspase-3 and apoptosis in cerebellar granule cells. J.Neurosci.Res. 52 334 PMID: 9590441
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Keywords: Fluorogenic caspase-1 ICE Caspases Proteinases Proteases Caspases
Citations for Ac-YVAD-AFC
Citations are publications that use Tocris products.
Currently there are no citations for Ac-YVAD-AFC.
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