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Discontinued ProductAc-IEPD-AFC (Cat. No. 1576) has been withdrawn from sale for commercial reasons.
Biological Activity for Ac-IEPD-AFC
Peptide sequence shown to be preferred recognition motif for the serine protease granzyme B. Fluorogenic substrate.
Technical Data for Ac-IEPD-AFC
(Modifications: Ile-1 = N-Ac-Ile, Asp-4 = Asp-(7-amino-4-trifluoromethylcoumarin))
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Ac-IEPD-AFC
References for Ac-IEPD-AFC
References are publications that support the biological activity of the product.
Thornberry et al (1997) A combinatorial approach defines specificities of members of the caspase family and granzyme B. J.Biol.Chem. 272 17907 PMID: 9218414
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Keywords: Ac-IEPD-AFC, Ac-IEPD-AFC supplier, Fluorogenic, granzyme, B, Caspases, Proteinases, Proteases, 1576, Tocris Bioscience
Citations for Ac-IEPD-AFC
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Currently there are no citations for Ac-IEPD-AFC.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cell Cycle and DNA Damage Research Product Guide
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Cell Cycle & DNA Damage Repair Poster
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Huntington's Disease Poster
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Programmed Cell Death Poster
There are two currently recognized forms of programmed cell death: apoptosis and necroptosis. This poster summarizes the signaling pathways involved in apoptosis, necroptosis and cell survival following death receptor activation, and highlights the influence of the molecular switch, cFLIP, on cell fate.