5-HT2B receptor selective agonist with pKi values of 8.4, 6.1 and 7.3 at 5-HT2B, 5-HT2A and 5-HT2C receptors respectively.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 306.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.26 mL||16.32 mL||32.65 mL|
|5 mM||0.65 mL||3.26 mL||6.53 mL|
|10 mM||0.33 mL||1.63 mL||3.26 mL|
|50 mM||0.07 mL||0.33 mL||0.65 mL|
References are publications that support the products' biological activity.
Baxter et al (1995) 5-HT2 receptor subtypes: a family re-united? TiPS 16 105 PMID: 7792930
Richardson et al (1985) Identification of serotonin M-receptor sub-types and their specific blockade by a new class of drugs. Nature 316 126 PMID: 3839291
Wilson et al (1990) 5-Hydroxytryptamine3 receptors mediate tachycardia in conscious instrumented dogs. J.Pharmacol.Exp.Ther. 252 683 PMID: 1968974
If you know of a relevant reference for α-Methyl-5-hydroxytryptamine maleate, please let us know.
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1 Citation for α-Methyl-5-hydroxytryptamine maleate
Citations are publications that use Tocris products. Selected citations for α-Methyl-5-hydroxytryptamine maleate include:
Coulon et al (2011) Activity Modes in Thalamocortical Relay Neurons are Modulated by G(q)/G(11) Family G-proteins - Serotonergic and Glutamatergic Signaling. Front Cell Neurosci 4 132 PMID: 21267426
Do you know of a great paper that uses α-Methyl-5-hydroxytryptamine maleate from Tocris? If so please let us know.
alpha-Methyl-5-hydroxytryptamine maleate Reviews
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