A 71623

Discontinued Product

A 71623 (Cat. No. 2036) has been withdrawn from sale for commercial reasons.
Cat.No. 2036 - A 71623 | C44H56N8O9 | CAS No. 130408-77-4
Description: Potent and selective CCK1agonist. Suppresses feeding
Chemical Name: N-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophyl-N6-[[(2-methylphenyl)amino]carbonyl]-L-lysyl-L-a-aspartyl-Na-methyl-L-phenylalaninamide
Datasheet
Citations
Reviews
Literature

Biological Activity

Potent CCK1 agonist (IC50 = 3.7 nM) with 1200-fold selectivity over the CCK2 receptor. Suppresses food intake following central or peripheral administration.

Technical Data

M. Wt 840.97
Formula C44H56N8O9
Storage Desiccate at -20°C
CAS Number 130408-77-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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References

References are publications that support the biological activity of the product.

Asin et al (1992) A-71623, a selective CCK-A receptor agonist, suppresses food intake in the mouse, dog, and monkey. Pharmacol.Biochem.Behav. 42 699 PMID: 1513850

DeNinno et al (1990) Development of CCK-tetrapeptide analogues as potent and selective CCK-A receptor agonists. J.Med.Chem. 33 2951

Lin et al (1990) Characterization of two novel cholecystokinin tetrapeptide (30-33) analogues, A-71623 and A-70874, that exhibit high potency and selectivity for cholecystokinin-A receptors. Mol.Pharmacol. 39 346

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Keywords: A 71623, A 71623 supplier, A-71623, CCK, CCK1, CCK-1, Obesity, Feeding, Anorexia, Cholecystokinin, CCK-8, Receptor, 2036, Tocris Bioscience

Citations for A 71623

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

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