You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Potent equilibrative nucleoside transporter 1 (ENT1) inhibitor (IC50 = 0.43 nM). Inhibits hENT1 and hENT2 uptake of [H3]uridine in K562 cells and K15NTD cells respectively.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 560.73. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||8.92 mL||44.58 mL||89.17 mL|
|1 mM||1.78 mL||8.92 mL||17.83 mL|
|2 mM||0.89 mL||4.46 mL||8.92 mL|
|10 mM||0.18 mL||0.89 mL||1.78 mL|
References are publications that support the biological activity of the product.
Lin et al (2011) Design, synthesis, and evaluation of 2-diethanolamino-4,8-diheptamethyleneimino-2-(N-aminoethyl-N-ethanolamino)-6-(N,N-diethanolamino)pyrimido[5,4-d]pyrimidine-fluorescein conjugate (8MDP-fluor), as a novel equilibrativ Bioconjug.Chem. 22 1221 PMID: 21539390
Lin et al (2007) Synthesis, flow cytometric evaluation, and identification of highly potent dipyrid. analogues as equilibrative nucleoside transporter 1 inhibitors. J.Med.Chem. 50 3906 PMID: 17636949
If you know of a relevant reference for 8MDP, please let us know.
View Related Products by Product Action
Keywords: 8MDP, 8MDP supplier, ENT1, inhibitors, inhibits, potent, equilibrative, nucleoside, transporters, 1, 2, ENT2, transports, Nucleoside, Transporters, 4588, Tocris Bioscience
Citations for 8MDP
Citations are publications that use Tocris products.
Currently there are no citations for 8MDP. Do you know of a great paper that uses 8MDP from Tocris? Please let us know.
Reviews for 8MDP
There are currently no reviews for this product. Be the first to review 8MDP and earn rewards!
Have you used 8MDP?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image