8-Cyclopentyl-1,3-dimethylxanthine

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Cat.No. 6137 - 8-Cyclopentyl-1,3-dimethylxanthine | C12H16N4O2 | CAS No. 35873-49-5
Description: High affinity adenosine A1 receptor antagonist
Alternative Names: CPT, 8-Cyclopentyltheophylline
Chemical Name: 8-Cyclopentyltheophylline
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

High affinity adenosine A1 receptor antagonist (pKi = 7.5-8).

Technical Data

M. Wt 248.28
Formula C12H16N4O2
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 35873-49-5
PubChem ID 1917
InChI Key SCVHFRLUNIOSGI-UHFFFAOYSA-N
Smiles CN1C2=C(C(N(C1=O)C)=O)N=C(C3CCCC3)N2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 24.83 100
ethanol 2.48 10

Preparing Stock Solutions

The following data is based on the product molecular weight 248.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.03 mL 20.14 mL 40.28 mL
5 mM 0.81 mL 4.03 mL 8.06 mL
10 mM 0.4 mL 2.01 mL 4.03 mL
50 mM 0.08 mL 0.4 mL 0.81 mL

Molarity Calculator

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References

References are publications that support the biological activity of the product.

Dalpiaz et al (1998) Thermodynamics of full agonist, partial agonist, and antagonist binding to wild-type and mutant adenosine A1 receptors. Biochem.Pharmacol. 56 1437 PMID: 9827575


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Keywords: 8-Cyclopentyl-1,3-dimethylxanthine, 8-Cyclopentyl-1,3-dimethylxanthine supplier, Adenosine, A1, receptors, antagonists, antagonism, high, affinity, CPT, 8-Cyclopentyltheophylline, Receptors, 6137, Tocris Bioscience

Citations for 8-Cyclopentyl-1,3-dimethylxanthine

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