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Description: High affinity adenosine A1 receptor antagonist
Alternative Names: CPT, 8-Cyclopentyltheophylline
Chemical Name: 8-Cyclopentyltheophylline
Purity: ≥99% (HPLC)
Literature (4)

Biological Activity for 8-Cyclopentyl-1,3-dimethylxanthine

8-Cyclopentyl-1,3-dimethylxanthine is a high affinity adenosine A1 receptor antagonist (pKi = 7.5-8).

Compound Libraries for 8-Cyclopentyl-1,3-dimethylxanthine

8-Cyclopentyl-1,3-dimethylxanthine is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for 8-Cyclopentyl-1,3-dimethylxanthine

M. Wt 248.28
Formula C12H16N4O2
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 35873-49-5
PubChem ID 1917
Smiles CN1C2=C(C(N(C1=O)C)=O)N=C(C3CCCC3)N2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for 8-Cyclopentyl-1,3-dimethylxanthine

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 24.83 100
ethanol 2.48 10

Preparing Stock Solutions for 8-Cyclopentyl-1,3-dimethylxanthine

The following data is based on the product molecular weight 248.28. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.03 mL 20.14 mL 40.28 mL
5 mM 0.81 mL 4.03 mL 8.06 mL
10 mM 0.4 mL 2.01 mL 4.03 mL
50 mM 0.08 mL 0.4 mL 0.81 mL

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Product Datasheets for 8-Cyclopentyl-1,3-dimethylxanthine

References for 8-Cyclopentyl-1,3-dimethylxanthine

References are publications that support the biological activity of the product.

Dalpiaz et al (1998) Thermodynamics of full agonist, partial agonist, and antagonist binding to wild-type and mutant adenosine A1 receptors. Biochem.Pharmacol. 56 1437 PMID: 9827575

If you know of a relevant reference for 8-Cyclopentyl-1,3-dimethylxanthine, please let us know.

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View all Adenosine A1 Receptor Antagonists

Keywords: 8-Cyclopentyl-1,3-dimethylxanthine, 8-Cyclopentyl-1,3-dimethylxanthine supplier, Adenosine, A1, receptors, antagonists, antagonism, high, affinity, CPT, 8-Cyclopentyltheophylline, Receptors, 6137, Tocris Bioscience

Citations for 8-Cyclopentyl-1,3-dimethylxanthine

Citations are publications that use Tocris products.

Currently there are no citations for 8-Cyclopentyl-1,3-dimethylxanthine. Do you know of a great paper that uses 8-Cyclopentyl-1,3-dimethylxanthine from Tocris? Please let us know.

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