Pricing Availability   Qty
Description: High affinity adenosine A1 receptor antagonist
Alternative Names: CPT,8-Cyclopentyltheophylline
Chemical Name: 8-Cyclopentyltheophylline
Purity: ≥99% (HPLC)

Biological Activity for 8-Cyclopentyl-1,3-dimethylxanthine

8-Cyclopentyl-1,3-dimethylxanthine is a high affinity adenosine A1 receptor antagonist (pKi = 7.5-8).

Compound Libraries for 8-Cyclopentyl-1,3-dimethylxanthine

8-Cyclopentyl-1,3-dimethylxanthine is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for 8-Cyclopentyl-1,3-dimethylxanthine

M. Wt 248.28
Formula C12H16N4O2
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 35873-49-5
PubChem ID 1917
Smiles CN1C2=C(C(N(C1=O)C)=O)N=C(C3CCCC3)N2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for 8-Cyclopentyl-1,3-dimethylxanthine

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 24.83 100
ethanol 2.48 10

Preparing Stock Solutions for 8-Cyclopentyl-1,3-dimethylxanthine

The following data is based on the product molecular weight 248.28. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.03 mL 20.14 mL 40.28 mL
5 mM 0.81 mL 4.03 mL 8.06 mL
10 mM 0.4 mL 2.01 mL 4.03 mL
50 mM 0.08 mL 0.4 mL 0.81 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets for 8-Cyclopentyl-1,3-dimethylxanthine

References for 8-Cyclopentyl-1,3-dimethylxanthine

References are publications that support the biological activity of the product.

Dalpiaz et al (1998) Thermodynamics of full agonist, partial agonist, and antagonist binding to wild-type and mutant adenosine A1 receptors. Biochem.Pharmacol. 56 1437 PMID: 9827575

If you know of a relevant reference for 8-Cyclopentyl-1,3-dimethylxanthine, please let us know.

View Related Products by Target

View Related Products by Product Action

View all Adenosine A1 Receptor Antagonists

Keywords: 8-Cyclopentyl-1,3-dimethylxanthine, 8-Cyclopentyl-1,3-dimethylxanthine supplier, Adenosine, A1, receptors, antagonists, antagonism, high, affinity, CPT, 8-Cyclopentyltheophylline, Receptors, 6137, Tocris Bioscience

Citations for 8-Cyclopentyl-1,3-dimethylxanthine

Citations are publications that use Tocris products.

Currently there are no citations for 8-Cyclopentyl-1,3-dimethylxanthine. Do you know of a great paper that uses 8-Cyclopentyl-1,3-dimethylxanthine from Tocris? Please let us know.

Reviews for 8-Cyclopentyl-1,3-dimethylxanthine

There are currently no reviews for this product. Be the first to review 8-Cyclopentyl-1,3-dimethylxanthine and earn rewards!

Have you used 8-Cyclopentyl-1,3-dimethylxanthine?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review