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Cat.No. 3859 - 6,2',4'-Trimethoxyflavone | C18H16O5 | CAS No. 720675-74-1
Description: Aryl hydrocarbon receptor antagonist
Chemical Name: 2',4',6-Trimethoxyflavone
Purity: ≥97% (HPLC)

Biological Activity

Aryl hydrocarbon receptor antagonist (EC50 = 0.9 μM). Exhibits no short term agonist activity and no species or promoter dependence.

Technical Data

M. Wt 312.32
Formula C18H16O5
Storage Store at RT
Purity ≥97% (HPLC)
CAS Number 720675-74-1
PubChem ID 688802
Smiles O=C1C3=C(C=CC(OC)=C3)OC(C2=CC=C(OC)C=C2OC)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 1.56 5mM with gentle warming

Preparing Stock Solutions

The following data is based on the product molecular weight 312.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.2 mL 16.01 mL 32.02 mL
5 mM 0.64 mL 3.2 mL 6.4 mL
10 mM 0.32 mL 1.6 mL 3.2 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet


References are publications that support the products' biological activity.

Murray et al (2010) Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone. J.Pharmacol.Exp.Ther. 332 135 PMID: 19828881

If you know of a relevant reference for 6,2',4'-Trimethoxyflavone, please let us know.

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Keywords: aryl hydrocarbon receptors antagonists AHR 6,2,4-Trimethoxyflavone Aryl Hydrocarbon Receptors

Citations for 6,2',4'-Trimethoxyflavone

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Nuclear Receptors

Nuclear Receptors Product Listing

A collection of over 150 products for key nuclear receptors, the listing includes research tools for the study of:

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