6,2',4'-Trimethoxyflavone

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Cat.No. 3859 - 6,2',4'-Trimethoxyflavone | C18H16O5 | CAS No. 720675-74-1
Description: Aryl hydrocarbon receptor antagonist
Chemical Name: 2',4',6-Trimethoxyflavone
Purity: ≥97% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Aryl hydrocarbon receptor antagonist (EC50 = 0.9 μM). Exhibits no short term agonist activity and no species or promoter dependence.

Technical Data

M. Wt 312.32
Formula C18H16O5
Storage Store at RT
Purity ≥97% (HPLC)
CAS Number 720675-74-1
PubChem ID 688802
InChI Key WUWFDVDASNSUKP-UHFFFAOYSA-N
Smiles O=C1C3=C(C=CC(OC)=C3)OC(C2=CC=C(OC)C=C2OC)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 1.56 5mM with gentle warming

Preparing Stock Solutions

The following data is based on the product molecular weight 312.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.2 mL 16.01 mL 32.02 mL
5 mM 0.64 mL 3.2 mL 6.4 mL
10 mM 0.32 mL 1.6 mL 3.2 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

Molarity Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Murray et al (2010) Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone. J.Pharmacol.Exp.Ther. 332 135 PMID: 19828881


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Keywords: aryl hydrocarbon receptors antagonists AHR 6,2,4-Trimethoxyflavone Aryl Hydrocarbon Receptors

Citations for 6,2',4'-Trimethoxyflavone

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Nuclear Receptors

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