5-Nonyloxytryptamine oxalate

Discontinued Product

5-Nonyloxytryptamine oxalate (Cat. No. 0901) has been withdrawn from sale for commercial reasons.
Description: Selective 5-HT1B agonist
Purity: ≥99% (HPLC)
Literature (2)

Biological Activity for 5-Nonyloxytryptamine oxalate

5-HT1B selective agonist, several times more potent than sumatriptan and inactive as a 5-HT1A agonist (Ki at 5-HT1B = 1 nM, selectivity over 5-HT1A > 300-fold). Mimics polysialic acid activity, stimulates neuritogenesis, myelination and Schwann cell migration in vitro.

Technical Data for 5-Nonyloxytryptamine oxalate

M. Wt 392.49
Formula C19H30N2O.C2H2O4
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 157798-13-5
PubChem ID 10126593

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for 5-Nonyloxytryptamine oxalate

Certificate of Analysis / Product Datasheet
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References for 5-Nonyloxytryptamine oxalate

References are publications that support the biological activity of the product.

Glennon et al (1994) 5-(Nonyloxy)tryptamine: a novel high affinity-5-HT1Dβ serotonin receptor agonist. J.Med.Chem. 37 2828 PMID: 8071931

Glennon et al (1996) Binding of O-Alkyl derivatives of serotonin at human 5-HT1Dβ receptors. J.Med.Chem. 39 314 PMID: 8568822

Loers et al (2013) Nonyloxytryptamine mimics polysialic acid and modulates neuronal and glial functions in cell culture. J.Neurochem. 128 88 PMID: 23957498

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Keywords: 5-Nonyloxytryptamine oxalate, 5-Nonyloxytryptamine oxalate supplier, Selective, 5-HT1B, agonists, Serotonin, Receptors, 0901, Tocris Bioscience

Citations for 5-Nonyloxytryptamine oxalate

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Currently there are no citations for 5-Nonyloxytryptamine oxalate.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

5-HT Receptors Scientific Review

5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.

Parkinson's Disease Poster

Parkinson's Disease Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.