5-Nonyloxytryptamine oxalate

Discontinued Product

5-Nonyloxytryptamine oxalate (Cat. No. 0901) has been withdrawn from sale for commercial reasons.
Cat.No. 0901 - 5-Nonyloxytryptamine oxalate | C19H30N2O.C2H2O4 | CAS No. 157798-13-5
Description: Selective 5-HT1B agonist
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

5-HT1B selective agonist, several times more potent than sumatriptan and inactive as a 5-HT1A agonist (Ki at 5-HT1B = 1 nM, selectivity over 5-HT1A > 300-fold). Mimics polysialic acid activity, stimulates neuritogenesis, myelination and Schwann cell migration in vitro.

Technical Data

M. Wt 392.49
Formula C19H30N2O.C2H2O4
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 157798-13-5
PubChem ID 10126593
InChI Key JORSCLBFSAAOFR-UHFFFAOYSA-N
Smiles OC(=O)C(O)=O.CCCCCCCCCOC1=CC=C2NC=C(CCN)C2=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Glennon et al (1994) 5-(Nonyloxy)tryptamine: a novel high affinity-5-HT1Dβ serotonin receptor agonist. J.Med.Chem. 37 2828 PMID: 8071931

Glennon et al (1996) Binding of O-Alkyl derivatives of serotonin at human 5-HT1Dβ receptors. J.Med.Chem. 39 314 PMID: 8568822

Loers et al (2013) Nonyloxytryptamine mimics polysialic acid and modulates neuronal and glial functions in cell culture. J.Neurochem. 128 88 PMID: 23957498

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Keywords: 5-Nonyloxytryptamine oxalate, 5-Nonyloxytryptamine oxalate supplier, Selective, 5-HT1B, agonists, Serotonin, Receptors, 0901, Tocris Bioscience

Citations for 5-Nonyloxytryptamine oxalate

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