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Description: Metabolic probe for labeling mycobacterium cell envelope
Chemical Name: 5-Azido-5-deoxy-myo-inositol
Purity: ≥90% (HPLC)

Biological Activity for 5-InoAz

5-InoAz is a metabolic probe for labeling the mycobacterium cell envelope. Specifically designed as an inositol analog to incorportate into cell envelope glycolipids (phosphatidylinositol mannoside (PIM), PIM-anchored lipomannan (LM) and lipoarabinomannan (LAM)). In combination with bioorthogonal chemistry, it provides a valuable tool for investigating PIM, LM, and LAM biosynthesis, transport, and dynamics in diverse mycobacterial organisms.

Technical Data for 5-InoAz

M. Wt 205.17
Formula C6H11N3O5
Storage Store at -20°C
Purity ≥90% (HPLC)
CAS Number 1218932-97-8
PubChem ID 102168607
Smiles O[C@@H]([C@@H]([C@@H]([C@@H]([C@H]1O)O)O)O)[C@H]1N=[N+]=[N-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for 5-InoAz

Solvent Max Conc. mg/mL Max Conc. mM
water 20.52 100
DMSO 20.52 100

Preparing Stock Solutions for 5-InoAz

The following data is based on the product molecular weight 205.17. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.87 mL 24.37 mL 48.74 mL
5 mM 0.97 mL 4.87 mL 9.75 mL
10 mM 0.49 mL 2.44 mL 4.87 mL
50 mM 0.1 mL 0.49 mL 0.97 mL

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References for 5-InoAz

References are publications that support the biological activity of the product.

Hodges et al (2023) Azido inositol probes enable metabolic labeling of inositol-containing glycans and reveal an inositol importer in mycobacteria. ACS Chem.Biol. 18 595 PMID: 36856664

If you know of a relevant reference for 5-InoAz, please let us know.

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Keywords: 5-InoAz, 5-InoAz supplier, metabolic, probe, analogue, labeling, bacteria, labels, labelling, imaging, mycobacteria, glycolipid, PIM, LM, LAM, bioorthogonal, chemistry, inositol, phosphatidylinositol, mannoside, anchored, lipomannan, lipoarabinomannan, Glycobiology, Probes, 7973, Tocris Bioscience

Citations for 5-InoAz

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