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Description: Metabolic probe for labeling mycobacterium cell envelope
Chemical Name: 5-Azido-5-deoxy-myo-inositol
Purity: ≥90% (HPLC)
Biological Activity for 5-InoAz
5-InoAz is a metabolic probe for labeling the mycobacterium cell envelope. Specifically designed as an inositol analog to incorportate into cell envelope glycolipids (phosphatidylinositol mannoside (PIM), PIM-anchored lipomannan (LM) and lipoarabinomannan (LAM)). In combination with bioorthogonal chemistry, it provides a valuable tool for investigating PIM, LM, and LAM biosynthesis, transport, and dynamics in diverse mycobacterial organisms.
Technical Data for 5-InoAz
| M. Wt | 205.17 |
| Formula | C6H11N3O5 |
| Storage | Store at -20°C |
| Purity | ≥90% (HPLC) |
| CAS Number | 1218932-97-8 |
| PubChem ID | 102168607 |
| InChI Key | KTRSBMDLCXWFCL-ZYNIPDFASA-N |
| Smiles | O[C@@H]([C@@H]([C@@H]([C@@H]([C@H]1O)O)O)O)[C@H]1N=[N+]=[N-] |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for 5-InoAz
References for 5-InoAz
References are publications that support the biological activity of the product.
Hodges et al (2023) Azido inositol probes enable metabolic labeling of inositol-containing glycans and reveal an inositol importer in mycobacteria. ACS Chem.Biol. 18 595 PMID: 36856664
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Keywords: 5-InoAz, 5-InoAz supplier, metabolic, probe, analogue, labeling, bacteria, labels, labelling, imaging, mycobacteria, glycolipid, PIM, LM, LAM, bioorthogonal, chemistry, inositol, phosphatidylinositol, mannoside, anchored, lipomannan, lipoarabinomannan, Glycobiology, Probes, Fluorescent, for, Imaging, Bacteria, 7973, Tocris Bioscience
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