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Cat.No. 0386 - 3-Methyl-GABA | C5H11NO2 | CAS No. 1216629-00-3
Description: Activator of GABA amino-transferase
Chemical Name: (±)-4-Amino-3-methylbutanoic acid hemi naphthalene-1,5-disulfonic acid
Literature (1)

Biological Activity

Activator of GABA aminotransferase. Anticonvulsant.

Technical Data

M. Wt 522.58
Formula C5H11NO2
Storage Store at RT
CAS Number 1216629-00-3
PubChem ID 57369841
Smiles CC(CN)CC(O)=O.CC(CN)CC(O)=O.OS(=O)(=O)C1=CC=CC2=C(C=CC=C12)S(O)(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
water 100

Preparing Stock Solutions

The following data is based on the product molecular weight 522.58. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.91 mL 9.57 mL 19.14 mL
5 mM 0.38 mL 1.91 mL 3.83 mL
10 mM 0.19 mL 0.96 mL 1.91 mL
50 mM 0.04 mL 0.19 mL 0.38 mL

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References are publications that support the biological activity of the product.

Silverman et al (1991) 3-Alkyl-4-aminobutyric acids: the first class of anticonvulsant agents that activate L-glutamic acid decarboxylase. J.Med.Chem. 34 2295 PMID: 2067001

If you know of a relevant reference for 3-Methyl-GABA, please let us know.

Keywords: 3-Methyl-GABA, 3-Methyl-GABA supplier, activators, GABA, amino-transferase, Transferases, Miscellaneous, GABAB, Receptors, Other, 0386, Tocris Bioscience

Citations for 3-Methyl-GABA

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Literature in this Area

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GABA Receptors

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.