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Cat.No. 0386 - 3-Methyl-GABA | C5H11NO2 | CAS No. 71424-95-8
Description: Activator of GABA amino-transferase
Chemical Name: (±)-4-Amino-3-methylbutanoic acid hemi naphthalene-1,5-disulfonic acid

Biological Activity

Activator of GABA aminotransferase. Anticonvulsant.

Technical Data

M. Wt 522.58
Formula C5H11NO2
Storage Store at RT
CAS Number 71424-95-8
PubChem ID 57369841
Smiles CC(CN)CC(O)=O.CC(CN)CC(O)=O.OS(=O)(=O)C1=CC=CC2=C(C=CC=C12)S(O)(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 522.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.91 mL 9.57 mL 19.14 mL
5 mM 0.38 mL 1.91 mL 3.83 mL
10 mM 0.19 mL 0.96 mL 1.91 mL
50 mM 0.04 mL 0.19 mL 0.38 mL

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Silverman et al (1991) 3-Alkyl-4-aminobutyric acids: the first class of anticonvulsant agents that activate L-glutamic acid decarboxylase. J.Med.Chem. 34 2295 PMID: 2067001

If you know of a relevant reference for 3-Methyl-GABA, please let us know.

Keywords: 3-Methyl-GABA, supplier, activators, GABA, amino-transferase, Transferases, Miscellaneous, GABA, GABAB, Receptors, Other, Transferases, Miscellaneous, GABA, Tocris Bioscience

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Literature in this Area

GABA Receptors

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.