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Cat.No. 0788 - 3-Aminobenzamide | C7H8N2O | CAS No. 3544-24-9
Description: PARP inhibitor
Alternative Names: 3-ABA

Biological Activity

An inhibitor of poly(ADP-ribose) polymerase, which protects cells from UV-B-induced apoptosis via influence on the cytoskeleton.

Compound Libraries

3-Aminobenzamide is also offered as part of the Tocriscreen Epigenetics Toolbox. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 136.15
Formula C7H8N2O
Storage Store at RT
CAS Number 3544-24-9
PubChem ID 1645
Smiles NC(=O)C1=CC=CC(N)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 136.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 7.34 mL 36.72 mL 73.45 mL
5 mM 1.47 mL 7.34 mL 14.69 mL
10 mM 0.73 mL 3.67 mL 7.34 mL
50 mM 0.15 mL 0.73 mL 1.47 mL

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Cuzzocrea et al (1997) Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion. Br.J.Pharmacol. 121 1065 PMID: 9249240

Malorni et al (1995) 3-Aminobenzamide protects cells from UV-B-induced apoptosis by acting on cytoskeleton and substrate adhesion. Biochem.Biophys.Res.Commun. 207 715 PMID: 7864864

If you know of a relevant reference for 3-Aminobenzamide, please let us know.

View Related Products by Product Action

View all Poly(ADP-Ribose) Polymerase Inhibitors

Keywords: 3-Aminobenzamide, supplier, PARP, inhibitors, inhibits, PolyADP-ribose, Polymerases, 3-ABA, Poly(ADP-ribose), Polymerase, Poly(ADP-ribose), Polymerase, Tocris Bioscience

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