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Description: PARP inhibitor
Alternative Names: 3-ABA
Citations (1)
Literature (4)

Biological Activity for 3-Aminobenzamide

3-Aminobenzamide is an inhibitor of poly(ADP-ribose) polymerase, which protects cells from UV-B-induced apoptosis via influence on the cytoskeleton.

Technical Data for 3-Aminobenzamide

M. Wt 136.15
Formula C7H8N2O
Storage Store at RT
CAS Number 3544-24-9
PubChem ID 1645
Smiles NC(=O)C1=CC=CC(N)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for 3-Aminobenzamide

Solvent Max Conc. mg/mL Max Conc. mM
water 100

Preparing Stock Solutions for 3-Aminobenzamide

The following data is based on the product molecular weight 136.15. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 7.34 mL 36.72 mL 73.45 mL
5 mM 1.47 mL 7.34 mL 14.69 mL
10 mM 0.73 mL 3.67 mL 7.34 mL
50 mM 0.15 mL 0.73 mL 1.47 mL

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Product Datasheets for 3-Aminobenzamide

References for 3-Aminobenzamide

References are publications that support the biological activity of the product.

Cuzzocrea et al (1997) Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion. Br.J.Pharmacol. 121 1065 PMID: 9249240

Malorni et al (1995) 3-Aminobenzamide protects cells from UV-B-induced apoptosis by acting on cytoskeleton and substrate adhesion. Biochem.Biophys.Res.Commun. 207 715 PMID: 7864864

If you know of a relevant reference for 3-Aminobenzamide, please let us know.

View Related Products by Product Action

View all Poly(ADP-Ribose) Polymerase Inhibitors

Keywords: 3-Aminobenzamide, 3-Aminobenzamide supplier, PARP, inhibitors, inhibits, PolyADP-ribose, Polymerases, 3-ABA, Poly(ADP-ribose), Polymerase, 0788, Tocris Bioscience

1 Citation for 3-Aminobenzamide

Citations are publications that use Tocris products. Selected citations for 3-Aminobenzamide include:

Pakula et al (2019) The Epithelial-Mesenchymal Transition Initiated by Malignant Ascites Underlies the Transmesothelial Invasion of Ovarian Cancer Cells. Int J Mol Sci 20 PMID: 30609691

Do you know of a great paper that uses 3-Aminobenzamide from Tocris? Please let us know.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

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