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Immunosuppressant. Inhibits [3H]-thymidine incorporation in the human mixed lymphocyte reaction. ED50 = 2.7 μM.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Crawford et al (1996) Rational design of novel immunosuppressive drugs: analogues of azathio. lacking the 6-mercaptopurine substituent retain or have enhanced immunosuppressive effects. J.Med.Chem. 39 2690 PMID: 8709098
Crawford et al (1995) Rational design of immunosuppressants: thioethers-azathioprine analogues without bone marrow toxicity. Br.J.Clin.Pharmacol. 40 508P
Keywords: 3-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-4-methyl-1,2,4-triazole, 3-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-4-methyl-1,2,4-triazole supplier, Miscellaneous, Compounds, 0564, Tocris Bioscience
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