2-TEDC

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Cat.No. 0645 - 2-TEDC | C16H13NO4S | CAS No. 132465-10-2
Description: 5-, 12-, 15-Lipoxygenase inhibitor
Chemical Name: 2-(1-Thienyl)ethyl 3,4-dihydroxybenzylidenecyanoacetate
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Potent inhibitor of 5-, 12-, and 15-lipoxygenase (IC50 values are 0.09, 0.013 and 0.5 μM respectively).

Technical Data

M. Wt 315.34
Formula C16H13NO4S
Storage Desiccate at +4°C
Purity ≥99% (HPLC)
CAS Number 132465-10-2
PubChem ID 6069552
InChI Key KCGLTUBCAGZLHP-XYOKQWHBSA-N
Smiles OC1=C(O)C=C(\C=C(/C#N)C(=O)OCCC2=CC=CS2)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 100 mM in DMSO and to 25 mM in ethanol

References

References are publications that support the biological activity of the product.

Cho et al (1991) Novel caffeic acid derivatives - extremely potent inhibitors of 12-lipoxygenase. J.Med.Chem. 34 1503 PMID: 2016727


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Keywords: 2-TEDC, 2-TEDC supplier, 5-lipoxygenase, 12-lipoxygenase, 15-Lipoxygenase, inhibitors, inhibits, Oxygenases, Oxidases, 5-LOX, 12-LOX, 15-LOX, Lipoxygenase, 0645, Tocris Bioscience

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