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Biological Activity for 2-TEDC
2-TEDC is a potent inhibitor of 5-, 12-, and 15-lipoxygenase (IC50 values are 0.09, 0.013 and 0.5 μM respectively).
Technical Data for 2-TEDC
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for 2-TEDC
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for 2-TEDC
The following data is based on the product molecular weight 315.34. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.17 mL||15.86 mL||31.71 mL|
|5 mM||0.63 mL||3.17 mL||6.34 mL|
|10 mM||0.32 mL||1.59 mL||3.17 mL|
|50 mM||0.06 mL||0.32 mL||0.63 mL|
References for 2-TEDC
References are publications that support the biological activity of the product.
Cho et al (1991) Novel caffeic acid derivatives - extremely potent inhibitors of 12-lipoxygenase. J.Med.Chem. 34 1503 PMID: 2016727
If you know of a relevant reference for 2-TEDC, please let us know.
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Keywords: 2-TEDC, 2-TEDC supplier, 5-lipoxygenase, 12-lipoxygenase, 15-Lipoxygenase, inhibitors, inhibits, Oxygenases, Oxidases, 5-LOX, 12-LOX, 15-LOX, Lipoxygenase, 0645, Tocris Bioscience
Citations for 2-TEDC
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Currently there are no citations for 2-TEDC. Do you know of a great paper that uses 2-TEDC from Tocris? Please let us know.
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