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Discontinued Product
0627 has been discontinued.
View all Adrenergic α<sub>1</sub> Receptors products.
Description: Potent, selective α1 antagonist
Chemical Name: 2-[(4-Phenylpiperazin-1-yl)methyl]-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one
Biological Activity for 2-PMDQ
Potent and selective α1-adrenoceptor antagonist and antihypertensive.
Technical Data for 2-PMDQ
| M. Wt | 361.45 |
| Formula | C21H23N5O |
| Storage | Store at RT |
| CAS Number | 139047-55-5 |
| PubChem ID | 6081682 |
| InChI Key | ONSOQRPYFKDOEB-UHFFFAOYSA-N |
| Smiles | O=C1NC2=C(C=CC=C2)C2=NC(CN3CCN(CC3)C3=CC=CC=C3)CN12 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for 2-PMDQ
Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service
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References for 2-PMDQ
References are publications that support the biological activity of the product.
Chern et al (1993) Studies on quinazolines. 5. 2,3-dihydroimidazo[1,2-c]quinazoline derivatives - a novel class of potent and selective α1-adrenoceptor antagonists and antihypertensive agents. J.Med.Chem. 36 2196 PMID: 8101878
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Keywords: 2-PMDQ, 2-PMDQ supplier, Potent, selective, α1-adrenoceptor, alpha1-adrenoceptor, α1-adrenergic, alpha1-adrenergic, a1-adrenergic, a1-adrenoceptor, antagonists, receptors, antihypertensive, Adrenergic, Alpha-1, Receptors, 0627, Tocris Bioscience
Citations for 2-PMDQ
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Currently there are no citations for 2-PMDQ.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.