You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
5-HT3 agonist (Ki = 1200 nM) and potent 5-HT6 ligand (Ki = 46 nM).
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 226.71. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.41 mL||22.05 mL||44.11 mL|
|5 mM||0.88 mL||4.41 mL||8.82 mL|
|10 mM||0.44 mL||2.21 mL||4.41 mL|
|50 mM||0.09 mL||0.44 mL||0.88 mL|
References are publications that support the biological activity of the product.
Craig et al (1990) 5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum. Naunyn Schmiedebergs Arch.Pharmacol. 342 9 PMID: 2402303
Glennon et al (2000) 2-substituted tryptamines: agents with selectivity for 5-HT6 serotonin receptors. J.Med.Chem. 43 1011 PMID: 10715164
Ismaiel et al (1990) 5-HT1 and 5-HT2 binding profiles of the serotonergic agents α-methyl serotonin and 2-methylserotonin. J.Med.Chem. 33 755 PMID: 2299641
Wilson et al (1990) 5-Hydroxytryptamine3 receptors mediate tachycardia in conscious instrumented dogs. J.Pharmacol.Exp.Ther. 252 683 PMID: 1968974
If you know of a relevant reference for 2-Methyl-5-hydroxytryptamine hydrochloride, please let us know.
View Related Products by Product Action
Keywords: 2-Methyl-5-hydroxytryptamine hydrochloride, 2-Methyl-5-hydroxytryptamine hydrochloride supplier, 5-HT3, agonists, potent, 5-HT6, ligand, Serotonin, Receptors, 2-Me-5HT, 2, methyl5HT, 0558, Tocris Bioscience
Citations for 2-Methyl-5-hydroxytryptamine hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for 2-Methyl-5-hydroxytryptamine hydrochloride. Do you know of a great paper that uses 2-Methyl-5-hydroxytryptamine hydrochloride from Tocris? Please let us know.
Reviews for 2-Methyl-5-hydroxytryptamine hydrochloride
There are currently no reviews for this product. Be the first to review 2-Methyl-5-hydroxytryptamine hydrochloride and earn rewards!
Have you used 2-Methyl-5-hydroxytryptamine hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.