An inhibitor of NO synthases, more potent than NG-methyl-L-arginine and selective for iNOS.
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 100 mM in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 134.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||7.43 mL||37.14 mL||74.29 mL|
|5 mM||1.49 mL||7.43 mL||14.86 mL|
|10 mM||0.74 mL||3.71 mL||7.43 mL|
|50 mM||0.15 mL||0.74 mL||1.49 mL|
References are publications that support the products' biological activity.
Moore et al (1996) 2-Iminopiperidine and other 2-iminoazaheterocycles as potent inhibitors of human nitric oxide synthase isoforms. J.Med.Chem. 39 669 PMID: 8576908
Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 18 204 PMID: 9226999
Southan et al (1995) Amidines are potent inhibitors of nitric oxide synthases: preferential inhibition of the inducible isoform. Eur.J.Pharmacol. 291 311 PMID: 8719415
If you know of a relevant reference for 2-Iminopiperidine hydrochloride, please let us know.
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Keywords: 2-Iminopiperidine hydrochloride, supplier, Selective, iNOS, inhibitors, inhibits, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, iNOS, iNOS, Tocris Bioscience
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