2-Iminopiperidine hydrochloride

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Cat.No. 0951 - 2-Iminopiperidine hydrochloride | C5H10N2.HCl | CAS No. 16011-96-4
Description: Selective iNOS inhibitor
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Citations
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Literature

Biological Activity

An inhibitor of NO synthases, more potent than NG-methyl-L-arginine and selective for iNOS.

Technical Data

M. Wt 134.61
Formula C5H10N2.HCl
Storage Desiccate at RT
CAS Number 16011-96-4
PubChem ID 85236
InChI Key ZHDTXTDHBRADLM-UHFFFAOYSA-N
Smiles N=C1NCCCC1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 134.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 7.43 mL 37.14 mL 74.29 mL
5 mM 1.49 mL 7.43 mL 14.86 mL
10 mM 0.74 mL 3.71 mL 7.43 mL
50 mM 0.15 mL 0.74 mL 1.49 mL

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Product Datasheets

Certificate of Analysis is currently unavailable
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Safety Datasheet

References

References are publications that support the products' biological activity.

Moore et al (1996) 2-Iminopiperidine and other 2-iminoazaheterocycles as potent inhibitors of human nitric oxide synthase isoforms. J.Med.Chem. 39 669 PMID: 8576908

Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 18 204 PMID: 9226999

Southan et al (1995) Amidines are potent inhibitors of nitric oxide synthases: preferential inhibition of the inducible isoform. Eur.J.Pharmacol. 291 311 PMID: 8719415


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Keywords: 2-Iminopiperidine hydrochloride, supplier, Selective, iNOS, inhibitors, inhibits, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, iNOS, iNOS, Tocris Bioscience

Citations for 2-Iminopiperidine hydrochloride

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