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An inhibitor of NO synthases, more potent than NG-methyl-L-arginine and selective for iNOS.
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 134.61. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||7.43 mL||37.14 mL||74.29 mL|
|5 mM||1.49 mL||7.43 mL||14.86 mL|
|10 mM||0.74 mL||3.71 mL||7.43 mL|
|50 mM||0.15 mL||0.74 mL||1.49 mL|
References are publications that support the biological activity of the product.
Moore et al (1996) 2-Iminopiperidine and other 2-iminoazaheterocycles as potent inhibitors of human nitric oxide synthase isoforms. J.Med.Chem. 39 669 PMID: 8576908
Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 18 204 PMID: 9226999
Southan et al (1995) Amidines are potent inhibitors of nitric oxide synthases: preferential inhibition of the inducible isoform. Eur.J.Pharmacol. 291 311 PMID: 8719415
If you know of a relevant reference for 2-Iminopiperidine hydrochloride, please let us know.
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Keywords: 2-Iminopiperidine hydrochloride, 2-Iminopiperidine hydrochloride supplier, Selective, iNOS, inhibitors, inhibits, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, 0951, Tocris Bioscience
Citations for 2-Iminopiperidine hydrochloride
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Literature in this Area
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