2-Amino-4-methylpyridine

Discontinued Product

2-Amino-4-methylpyridine (Cat. No. 1020) has been withdrawn from sale for commercial reasons.
Description: iNOS inhibitor
Datasheet
Citations
Reviews
Literature (1)

Biological Activity for 2-Amino-4-methylpyridine

A potent inhibitor of iNOS derived from mouse RAW 264.7 cells (IC50 = 6 nM), although less potent on human recombinant NOS isozymes with IC50 values of 100, 40 and 90 nM at nNOS, iNOS and eNOS respectively. Active in vivo, it shows 6.9-fold selectivity for iNOS vs. eNOS in conscious rats.

Technical Data for 2-Amino-4-methylpyridine

M. Wt 108.14
Storage Store at RT
CAS Number 695-34-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for 2-Amino-4-methylpyridine

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References for 2-Amino-4-methylpyridine

References are publications that support the biological activity of the product.

Faraci et al (1996) 2-Amino-4-methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivo. Br.J.Pharmacol. 119 1101 PMID: 8937711

Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPs 18 204 PMID: 9226999

Merck Index 12 486

View Related Products by Target

View Related Products by Product Action

View all iNOS Inhibitors

Keywords: 2-Amino-4-methylpyridine, 2-Amino-4-methylpyridine supplier, iNOS, 1020, Tocris Bioscience

Citations for 2-Amino-4-methylpyridine

Citations are publications that use Tocris products.

Currently there are no citations for 2-Amino-4-methylpyridine.

Reviews for 2-Amino-4-methylpyridine

There are currently no reviews for this product. Be the first to review 2-Amino-4-methylpyridine and earn rewards!

Have you used 2-Amino-4-methylpyridine?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer Research Product Guide

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis