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Description: LTB ω-hydroxylase inhibitor
Chemical Name: 17-Octadecynoic acid
Purity: ≥95% (HPLC)
Citations (1)

Biological Activity for 17-ODYA

17-ODYA is a potent suicide inhibitor of LTB4 ω-hydroxylase.

Compound Libraries for 17-ODYA

17-ODYA is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for 17-ODYA

M. Wt 280.45
Formula C18H32O2
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 34450-18-5
PubChem ID 1449

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for 17-ODYA

Solvent Max Conc. mg/mL Max Conc. mM
ethanol 14.02 50
DMSO 28.05 100

Preparing Stock Solutions for 17-ODYA

The following data is based on the product molecular weight 280.45. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.57 mL 17.83 mL 35.66 mL
5 mM 0.71 mL 3.57 mL 7.13 mL
10 mM 0.36 mL 1.78 mL 3.57 mL
50 mM 0.07 mL 0.36 mL 0.71 mL

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Product Datasheets for 17-ODYA

Certificate of Analysis / Product Datasheet
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References for 17-ODYA

References are publications that support the biological activity of the product.

Edwards et al (1996) Effects of cytochrome P450 inhibitors on potassium currents and mechanical activity in rat portal vein. Br.J.Pharmacol. 119 691 PMID: 8904643

Shak et al (1985) Leukotriene B4 ω-hydroxylase in human polymorphonuclear leukocytes. J.Biol.Chem. 260 13023 PMID: 2997155

If you know of a relevant reference for 17-ODYA, please let us know.

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Keywords: 17-ODYA, 17-ODYA supplier, LTB-omega-Hydroxylase, inhibitors, inhibits, LTB-w-hydroxylase, Hydroxylases, Leukotriene, and, Related, Receptors, 0607, Tocris Bioscience

1 Citation for 17-ODYA

Citations are publications that use Tocris products. Selected citations for 17-ODYA include:

Pearson et al (2009) Detection of EETs and HETE-generating cytochrome P-450 enzymes and the effects of their metabolites on myometrial and vascular function. Am J Physiol Endocrinol Metab 297 E647 PMID: 19549792

Do you know of a great paper that uses 17-ODYA from Tocris? Please let us know.

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