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Cat.No. 1258 - 1-Deoxynojirimycin | C6H13NO4 | CAS No. 19130-96-2
Description: Glucosidase I and II inhibitor
Chemical Name: (2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol
Reviews (1)

Biological Activity for 1-Deoxynojirimycin

1-Deoxynojirimycin is an inhibitor of glucosidase I (Ki = 2.1 mM) and II (Ki = 7 mM).

Technical Data for 1-Deoxynojirimycin

M. Wt 163.17
Formula C6H13NO4
Storage Store at +4°C
CAS Number 19130-96-2
PubChem ID 29435
Smiles OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for 1-Deoxynojirimycin

Solvent Max Conc. mg/mL Max Conc. mM
water 16.32 100

Preparing Stock Solutions for 1-Deoxynojirimycin

The following data is based on the product molecular weight 163.17. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 6.13 mL 30.64 mL 61.29 mL
5 mM 1.23 mL 6.13 mL 12.26 mL
10 mM 0.61 mL 3.06 mL 6.13 mL
50 mM 0.12 mL 0.61 mL 1.23 mL

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Product Datasheets for 1-Deoxynojirimycin

Certificate of Analysis / Product Datasheet
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References for 1-Deoxynojirimycin

References are publications that support the biological activity of the product.

Bause et al (1989) Purification and characterization of trimming glucosidase I from pig liver. Eur.J.Biochem. 183 661 PMID: 2673780

Fuhrmann et al (1985) Inhibitors of oligosaccharide processing. Biochim.Biophys.Acta 825 95 PMID: 3159432

Hentges and Bause (1997) Affinity purification and characterization of glucosidase II from pig liver. Biol.Chem. 378 1031 PMID: 9348113

If you know of a relevant reference for 1-Deoxynojirimycin, please let us know.

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Keywords: 1-Deoxynojirimycin, 1-Deoxynojirimycin supplier, Glucosidase, I, II, inhibitors, inhibits, Glycosylases, Carbohydrate, Metabolism, α-glucosidase, alpha-glucosidase, a-glucosidase, antibiotics, Antibiotics, 1258, Tocris Bioscience

Citations for 1-Deoxynojirimycin

Citations are publications that use Tocris products.

Currently there are no citations for 1-Deoxynojirimycin. Do you know of a great paper that uses 1-Deoxynojirimycin from Tocris? Please let us know.

Reviews for 1-Deoxynojirimycin

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1-Deoxynojirimycin used in the antiviral studies.
By Anonymous on 01/24/2019
Species: Human

Our lab uses 1-Deoxynojirimycin in the antiviral studies. Measurable antiviral properties of the product makes it a very control compound.

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