CCG 2046

Cat. No. 2974

CCG 2046 C11H10N4 [13017-69-1]

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Chemical Name: 3-Methyl-3-propyl-1,1,2,2-cyclopropanetetracarbonitrile

Biological Activity

Inhibitor of regulator of G-protein signaling 4 (RGS4). Reduces the RGS4-Gαo protein-protein interaction signal.

Technical Data

M.Wt:
198.22
Formula:
C11H10N4
Solubility:
Soluble to 100 mM in DMSO
Purity:
>99 %
Storage:
Desiccate at +4°C
CAS No:
13017-69-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Roman et al (2007) Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay. Mol.Pharmacol. 71 169. PMID: 17012620.

If you know of a relevant reference for CCG 2046 please let us know.

Citations are publications that use Tocris products. Selected citations for CCG 2046 include:

Leister et al (2011) Two High Throughput Screen Assays for Measurement of TNF-α in THP-1 Cells. Curr Chem Genomics 5 21. PMID: 21643507.

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Keywords: CCG 2046, supplier, inhibitors, inhibits, regulator, G-protein, signaling, 4, RGS4, Gao, Heterotrimeric, CCG2046, Tocris Bioscience, G Protein (Heterotrimeric) Inhibitor products

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