Cat. No. 4641
Chemical Name: 2-Methyl-1-[(2-methyl-5-nitrophenyl
Biological ActivityHepatocyte nuclear factor 4α (HNF4α) antagonist. Represses expression of known HNF4α target genes. Decreases HNF4α DNA binding. Exhibits cytotoxic activity in a range of tumor cell lines, including human hepatocellular carcinoma.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Kiselyuk et al (2012) HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter. Chem.Biol. 19 806. PMID: 22840769.
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Keywords: BI 6015, supplier, BI6015, Hepatocyte, nuclear, factor, 4, alpha, HNF4a, HNF4α, antagonists, DNA, binding, cancer, Tocris Bioscience, Other Transcription Factor products
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