Quinelorane hydrochloride

Cat. No. 1519

Quinelorane hydrochloride C14H22N4.2HCl [97548-97-5]

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Alternative Name: LY 163502

Chemical Name: (5aR,9aR)-5,5a,6,7,8,9,9a,10-Octahydro-6-propylpyrido[2,3-g]quinazolin-2-amine dihydrochloride

Biological Activity

Dopamine D2 and D3 receptor agonist; Ki values are 5.7 and 3.4 nM respectively.

Licensing Information

Sold with the permission of Eli Lilly and Company

Technical Data

M.Wt:
319.27
Formula:
C14H22N4.2HCl
Solubility:
Soluble to 25 mM in water
Purity:
>99 %
Storage:
Desiccate at RT
CAS No:
97548-97-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Flietstra and Levant (1998) Comparison of D2 and D3 dopamine receptor affinity of dopaminergic compounds in the rat brain. Life Sci. 62 1825. PMID: 9600324.

Eaton et al (1994) Effects of the selective dopaminergic D2 agonist quinelorane on the activity of dopaminergic and noradrenergic neurons projecting to the diencephalon of the rat. J.Pharmacol.Exp.Ther. 268 645. PMID: 7906734.

Foreman et al (1989) Preclinical studies on quinelorane, a potent and highly selective D2-dopaminergic agonist. J.Pharmacol.Exp.Ther. 250 227. PMID: 2526214.

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Keywords: Quinelorane hydrochloride, supplier, D2, D3, agonists, Dopamine, D2-like, Non-Selective, Receptors, dopaminergic, LY163502, Tocris Bioscience, Non-selective Dopamine Agonist products

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