Cat. No. 4057
Chemical Name: 4-[3-[2-(Trifluoromethyl)-9H-thioxa
Biological ActivityAntipsychotic drug. Exhibits antagonistic activity at dopamine D1-5 receptors. Used in schizophrenia treatment.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Peuch et al (1981) Pharmacological properties of new antipsychotic agents: Use of animal models. Neuropharmacology 20 1279. PMID: 6119637.
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Citations are publications that use Tocris products. Selected citations for Flupenthixol dihydrochloride include:
Regna et al (2016) A critical role for the Drosophila dopamine D1-like receptor Dop1R2 at the onset of metamorphosis. PLoS One 16 15. PMID: 27184815.
FitzGerald et al (2014) A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response. PLoS One 9 e98891. PMID: 24902048.
Schulz et al (2012) First and second generation antipsychotics influence hippocampal gamma oscillations by interactions with 5-HT3 and D3 receptors. Br J Pharmacol 167 1480. PMID: 22817643.
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Keywords: Flupenthixol dihydrochloride, supplier, Flupenthixol, 2HCl, dopamine, receptor, antagonist, antipsychotic, drug, schizophrenia, Tocris Bioscience, Non-selective Dopamine Antagonist products