Discontinued Product

Unfortunately (Z)-Capsaicin (Cat. No. 0463) has been withdrawn from sale for commercial reasons.
Cat.No. 0463 - (Z)-Capsaicin | C18H27NO3 | CAS No. 25775-90-0
Description: Cis isomer of (E)-Capsaicin (Cat. No. 0462)
Chemical Name: (Z)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide

Biological Activity

The cis-isomer of capsaicin.

Technical Data

M. Wt 305.42
Formula C18H27NO3
Storage Store at RT
CAS Number 25775-90-0
Smiles COc1cc(CNC(CCCCC=CC(C)C)=O)ccc1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 305.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.27 mL 16.37 mL 32.74 mL
5 mM 0.65 mL 3.27 mL 6.55 mL
10 mM 0.33 mL 1.64 mL 3.27 mL
50 mM 0.07 mL 0.33 mL 0.65 mL

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Product Datasheets

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Safety Datasheet


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Pain Research Product Guide

A collection of over 250 products for pain research, the guide includes research tools for the study of:

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  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling

Pain Poster

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.