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YS-035 hydrochloride

Cat. No. 0416 Submit a Review Datasheet / COA / SDS
Pricing Availability   Qty
Description: Inhibits K+ outward/pacemaker current
Chemical Name: N,N-Bis-(3,4-dimethoxyphenylethyl)-N-methylamine hydrochloride
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Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for YS-035 hydrochloride

YS-035 hydrochloride is a Ca2+ blocker that strikingly prolongs cardiac action potentials by inhibiting pacemaker current and K+ outward currents.

Technical Data for YS-035 hydrochloride

M. Wt 395.93
Formula C21H29NO4.HCl
Storage Desiccate at RT
CAS Number 89805-39-0
PubChem ID 56017
InChI Key GYBONEHHSUABAO-UHFFFAOYSA-N
Smiles Cl.COC1=CC=C(CCN(C)CCC2=CC=C(OC)C(OC)=C2)C=C1OC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for YS-035 hydrochloride

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 100

Preparing Stock Solutions for YS-035 hydrochloride

The following data is based on the product molecular weight 395.93. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.53 mL 12.63 mL 25.26 mL
5 mM 0.51 mL 2.53 mL 5.05 mL
10 mM 0.25 mL 1.26 mL 2.53 mL
50 mM 0.05 mL 0.25 mL 0.51 mL

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Product Datasheets for YS-035 hydrochloride

Certificate of Analysis / Product Datasheet
Safety Datasheet

References for YS-035 hydrochloride

References are publications that support the biological activity of the product.

Berger et al (1991) Inhibition of potassium outward currents and pacemaker current in sheep cardiac Purkinje fibres by the vera. derivative YS-035. Naunyn Schmiedebergs Arch.Pharmacol. 344 653 PMID: 1775198

Deana et al (1984) Properties of a new calcium ion antagonist on cellular uptake and mitochondrial efflux of calcium ions. Biochem.J. 218 899 PMID: 6721841

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Citations for YS-035 hydrochloride

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