Potent chemokine receptor type 4 (CXCR4) antagonist (EC50 = 0.3 nM). Inhibits CXCR4/stromal cell-derived factor-1 (SDF-1)-mediated modulation of cAMP in vitro (EC50 = 1.2 nM).
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 290.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.44 mL||17.22 mL||34.44 mL|
|5 mM||0.69 mL||3.44 mL||6.89 mL|
|10 mM||0.34 mL||1.72 mL||3.44 mL|
|50 mM||0.07 mL||0.34 mL||0.69 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Zhan et al (2007) Discovery of small molecule CXCR4 antagonists. J.Med.Chem. 50 5655 PMID: 17958344
If you know of a relevant reference for WZ 811, please let us know.
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Keywords: WZ 811, supplier, WZ811, chemokine, receptors, receptor, type, 4, antagonists, CXCR4, Chemokine, CXC, Receptors, Chemokine, CXC, Receptors, Tocris Bioscience
Citations for WZ 811
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