You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Selective agonist for the formyl peptide receptors FPR2 and FPR3, expressed on immune cells. EC50 values for induction of calcium mobilization in FPR2-HL-60 cells and FPR3-HL-60 cells are 2 and 80 nM respectively.
(Modifications: Met-6 = C-terminal amide)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 0.60 mg/ml in water|
References are publications that support the biological activity of the product.
Baek et al (1996) Identification of the peptides that stimulate the phosphoinositide hydrolysis in lymphocyte cell lines from peptide libraries. J.Biol.Chem. 271 8170 PMID: 8626507
Christophe et al (2001) The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/Lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J.Biol.Chem. 276 21585 PMID: 11285256
Christophe et al (2002) Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1 /LXA4R, is not affected by lipoxin. Scand.J.Immunol. 56 470 PMID: 12410796
If you know of a relevant reference for WKYMVM, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: WKYMVM, WKYMVM supplier, Selective, FPR2, FPR3, receptor, agonists, FPRL, Formyl, like, Peptide, Receptors, W-peptide, 1799, Tocris Bioscience
4 Citations for WKYMVM
Citations are publications that use Tocris products. Selected citations for WKYMVM include:
Schepetkin et al (2013) 3-(1H-indol-3-yl)-2-[3-(4-nitrophenyl)ureido]propanamide enantiomers with human formyl-peptide receptor agonist activity: molecular modeling of chiral recognition by FPR2. Biochem Pharmacol 85 404 PMID: 23219934
Schepetkin et al (2011) Gastrin-releasing peptide/neuromedin B receptor antagonists PD176252, PD168368, and related analogs are potent agonists of human formyl-peptide receptors. Mol Pharmacol 79 77 PMID: 20943772
García-Prieto et al (2017) Neutrophil stunning by MP reduces infarct size. Nat Commun 8 14780 PMID: 28416795
Schepetkin et al (2014) Antagonism of human formyl peptide receptor 1 (FPR1) by chromones and related isoflavones. Biochem Pharmacol 92 627 PMID: 25450672
Do you know of a great paper that uses WKYMVM from Tocris? Please let us know.
Reviews for WKYMVM
There are currently no reviews for this product. Be the first to review WKYMVM and earn rewards!
Have you used WKYMVM?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.