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Submit ReviewWAY 207024 dihydrochloride
Discontinued Product
3890 has been discontinued.
View all Gonadotropin-Releasing Hormone Receptors products.
Description: GnRH receptor antagonist
Chemical Name: 6-[[4-[2-[4-(1,1-Dimethylethyl)phenyl]-1H-benzimidazol-7-yl]-i-piperazinyl]methyl]-quinoxaline dihydrochloride
Purity: ≥99% (HPLC)
Biological Activity for WAY 207024 dihydrochloride
WAY 207024 dihydrochloride is a gonadotropin releasing hormone receptor (GnRH-R) antagonist. Exhibits potent affinity (IC50 values are 12 and 71 nM for human and rat GnRH receptors respectively). Lowers plasma leuteinizing hormone levels in the rat. Orally active.
Licensing Information
Sold for research purposes under agreement from Pfizer Inc.
Technical Data for WAY 207024 dihydrochloride
| M. Wt | 549.54 |
| Formula | C30H32N6.2HCl |
| Storage | Desiccate at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 872002-73-8 |
| PubChem ID | 69403574 |
| InChI Key | REQCNTGYEABOIT-UHFFFAOYSA-N |
| Smiles | CC(C)(C)C(C=C6)=CC=C6C(N5)=NC1=C5C(N(CC4)CCN4CC2=CC=C(N=CC=N3)C3=C2)=CC=C1.Cl.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for WAY 207024 dihydrochloride
References for WAY 207024 dihydrochloride
References are publications that support the biological activity of the product.
Pelletier et al (2009) Discovery of 6-({4-[2-(4-tert-butylphenyl)-1H-benzimidazol-4-yl]piperazin-1-yl}methyl)quinoxaline (WAY-207024): an orally active antagonist of the g.tropin releasing hormone receptor (GnRH-R). J.Med.Chem. 52 214 PMID: 19072222
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Citations for WAY 207024 dihydrochloride
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