W-9 hydrochloride

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Cat.No. 0370 - W-9 hydrochloride | C16H21ClN2O2S.HCl | CAS No. 69762-85-2
Description: Calmodulin antagonist
Chemical Name: N-(6-Aminohexyl)-5-chloro-2-naphthalenesulfonamide hydrochloride
Datasheet
Citations

Biological Activity

Calmodulin antagonist (inhibits calmodulin-activated PDE activity with an IC50 of 72 μM).

Technical Data

M. Wt 377.33
Formula C16H21ClN2O2S.HCl
Storage Store at RT
CAS Number 69762-85-2
PubChem ID 2735339
InChI Key FGWDLQXTCSKXSK-UHFFFAOYSA-N
Smiles Cl.NCCCCCCNS(=O)(=O)C1=CC=C2C(Cl)=CC=CC2=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 25 mM in ethanol

Preparing Stock Solutions

The following data is based on the product molecular weight 377.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.65 mL 13.25 mL 26.5 mL
5 mM 0.53 mL 2.65 mL 5.3 mL
10 mM 0.27 mL 1.33 mL 2.65 mL
50 mM 0.05 mL 0.27 mL 0.53 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Hidaka et al (1979) Selective inhibitors of Ca2+-binding modulator of phosphodiesterase produce vascular relaxation and inhibit actin-myosin interaction. Mol.Pharmacol. 15 49 PMID: 218093

Hidaka et al (1981) N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc.Natl.Acad.Sci.U.S.A. 78 4354 PMID: 6945588


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