You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Discontinued ProductW-12 hydrochloride (Cat. No. 0363) has been withdrawn from sale for commercial reasons.
Biological Activity for W-12 hydrochloride
Calmodulin antagonist; less active analogue of W-13 (0361). Inhibits calmodulin activated PDE activity with an IC50 of 260 μM.
Technical Data for W-12 hydrochloride
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for W-12 hydrochloride
References for W-12 hydrochloride
References are publications that support the biological activity of the product.
Bosch et al (1998) Calmodulin inhibitor W13 induces sustained activation of ERK2 and expression of p21cip1. J.Biol.Chem. 273 22145 PMID: 9705360
Hidaka et al (1981) N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc.Natl.Acad.Sci.U.S.A. 78 4354 PMID: 6945588
Schofl et al (1999) Ca2+/calmodulin inhibition and phospholipase C-linked Ca2+ signaling in clonal β-cells. Endocrinology 140 5516 PMID: 10579314
View Related Products by Product Action
Keywords: W-12 hydrochloride, W-12 hydrochloride supplier, Calcium, Binding, Protein, 0363, Tocris Bioscience
Citations for W-12 hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for W-12 hydrochloride.
Reviews for W-12 hydrochloride
There are currently no reviews for this product. Be the first to review W-12 hydrochloride and earn rewards!
Have you used W-12 hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image