VUF 10460

Discontinued Product

VUF 10460 (Cat. No. 4769) has been withdrawn from sale for commercial reasons.
Cat.No. 4769 - VUF 10460 | C15H19N5 | CAS No. 1028327-66-3
Description: Selective H4 agonist
Chemical Name: 4-(4-Methyl-1-piperazinyl)-6-phenyl-2-Pyrimidinamine
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (3)

Biological Activity for VUF 10460

VUF 10460 is a selective histamine H4 receptor agonist; displays 50-fold selectivity for the rat H4 receptor over the H3 subtype (pKi values are 5.75 and 7.46 for rat H3 and H4 receptors respectively). Also exhibits affinity for the human H4 receptor (pKi = 8.22).

Technical Data for VUF 10460

M. Wt 269.34
Formula C15H19N5
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 1028327-66-3
PubChem ID 25129523
InChI Key NIJGWJIOMPHDBP-UHFFFAOYSA-N
Smiles NC1=NC(C2=CC=CC=C2)=CC(N3CCN(C)CC3)=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Keywords: VUF 10460, VUF 10460 supplier, VUF10460, histamine, histaminergic, H4, receptors, agonists, selective, Histamine, Receptors, 4769, Tocris Bioscience

Citations for VUF 10460

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