Voriconazole

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Cat.No. 3760 - Voriconazole | C16H14F3N5O | CAS No. 137234-62-9
Description: Triazole antifungal agent
Alternative Names: UK 109496
Chemical Name: (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-((1H)-1,2,4-triazol-1-yl)-butan-2-ol
Purity: ≥99% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Triazole antifungal agent. Displays potent activity against Candida, Cryptococcus and Aspergillus species.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Technical Data

M. Wt 349.31
Formula C16H14F3N5O
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 137234-62-9
PubChem ID 71616
InChI Key BCEHBSKCWLPMDN-MGPLVRAMSA-N
Smiles O[C@]([C@@H](C)C2=NC=NC=C2F)(C3=C(F)C=C(F)C=C3)CN1C=NC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 34.93 100
ethanol 34.93 100

Preparing Stock Solutions

The following data is based on the product molecular weight 349.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.86 mL 14.31 mL 28.63 mL
5 mM 0.57 mL 2.86 mL 5.73 mL
10 mM 0.29 mL 1.43 mL 2.86 mL
50 mM 0.06 mL 0.29 mL 0.57 mL

Molarity Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Marco et al (1998) In vitro activities of voriconazole (UK-190-496) and four other antifungal agents against 394 clinical isolates of Candida spp. Antimicrob.Agents Chemother. 42 161 PMID: 9449278

Kappe (1999) Antifungal activity of the new azole UK-109,496 (voriconazole). Mycoses 42 82 PMID:


If you know of a relevant reference for Voriconazole, please let us know.

View Related Products by Target

Keywords: UK109496 monotriazole antifungal agent Miscellaneous Pfizer UK 109496 Miscellaneous Compounds

Citations for Voriconazole

Citations are publications that use Tocris products.

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Literature in this Area

New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

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Pathways for Voriconazole

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