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Submit ReviewVoriconazole
Description: Triazole antifungal agent
Alternative Names: UK 109496
Chemical Name: (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-((1H)-1,2,4-triazol-1-yl)-butan-2-ol
Purity: ≥98% (HPLC)
Biological Activity for Voriconazole
Voriconazole is a triazole antifungal agent. Displays potent activity against Candida, Cryptococcus and Aspergillus species.
Licensing Information
Sold for research purposes under agreement from Pfizer Inc.
Technical Data for Voriconazole
| M. Wt | 349.31 |
| Formula | C16H14F3N5O |
| Storage | Store at +4°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 137234-62-9 |
| PubChem ID | 71616 |
| InChI Key | BCEHBSKCWLPMDN-MGPLVRAMSA-N |
| Smiles | O[C@]([C@@H](C)C2=NC=NC=C2F)(C3=C(F)C=C(F)C=C3)CN1C=NC=N1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Voriconazole
References for Voriconazole
References are publications that support the biological activity of the product.
Marco et al (1998) In vitro activities of voricon. (UK-190-496) and four other antifungal agents against 394 clinical isolates of Candida spp. Antimicrob.Agents Chemother. 42 161 PMID: 9449278
Kappe (1999) Antifungal activity of the new azole UK-109,496 (voriconazole). Mycoses 42 82
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Keywords: Voriconazole, Voriconazole supplier, UK109496, monotriazole, antifungal, agent, Miscellaneous, Pfizer, UK, 109496, Antifungals, 3760, Tocris Bioscience
1 Citation for Voriconazole
Citations are publications that use Tocris products. Selected citations for Voriconazole include:
Gyorgy et al (2022) Bile acid- and ethanol-mediated activation of Orai1 damages pancreatic ductal secretion in acute pancreatitis. J Physiol 600 1631-1650 PMID: 35081662
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