VKGILS-NH2

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Cat.No. 3392 - VKGILS-NH2 | Val-Lys-Gly-Ile-Leu-Ser-NH2 | CAS No. 942413-05-0
Description: Control peptide for SLIGKV-NH2 (Cat. No. 3010)
Datasheet
Citations

Biological Activity

Reversed amino acid sequence control peptide for SLIGKV-NH2 (Cat. No. 3010), a protease-activated receptor 2 (PAR2) agonist.

Technical Data

M. Wt 614.79
Formula C28H54N8O7
Sequence VKGILS

(Modifications: Ser-6 = C-terminal amide)

Storage Store at -20°C
CAS Number 942413-05-0
PubChem ID 90488839
InChI Key IYJUKRSADJIIBX-WAUHAFJUSA-N
Smiles [H]N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 2 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 614.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.63 mL 8.13 mL 16.27 mL
5 mM 0.33 mL 1.63 mL 3.25 mL
10 mM 0.16 mL 0.81 mL 1.63 mL
50 mM 0.03 mL 0.16 mL 0.33 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Tognetto et al (2000) Evidence that PAR-1 and PAR-2 mediate prostanoid-dependent contraction in isolated guinea-pig gallbladder. Br.J.Pharmacol. 131 689 PMID: 11030717

Huang (2007) Protease-activated receptor-1 (PAR1) and PAR2 but not PAR4 mediate relaxations in lower esophageal sphincter. Regul.Pept. 142 37 PMID: 17335921

Lin et al (2008) Protease-activated receptor-2 (PAR-2) is a weak enhancer of mucin secretion by human bronchial epithelial cells in vitro. Int.J.Biochem.Cell Biol. 40 1379 PMID: 18077203


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Keywords: Control peptide SLIGKV-NH2 PAR Receptors Protease-Activated proteinase-activated Protease-Activated Receptors

Citations for VKGILS-NH2

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