VIP (human, rat, mouse, rabbit, canine, porcine)

Pricing Availability   Qty
Cat.No. 1911 - VIP (human, rat, mouse, rabbit, canine, porcine) | His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2 | CAS No. 40077-57-4
Description: Involved in neurotransmission and smooth muscle relaxation
Alternative Names: Vasoactive Intestinal Peptide (human, rat, mouse, rabbit, canine, porcine)
Datasheet
Citations (2)
Reviews (1)
Literature

Biological Activity

Neuropeptide with many biological actions; plays a role in neurotransmission, smooth muscle relaxation and has trophic and mitogenic actions.

Technical Data

M. Wt 3325.83
Formula C147H238N44O42S
Sequence HSDAVFTDNYTRLRKQMAVKKYLNSILN

(Modifications: Asn-28 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 40077-57-4
PubChem ID 16140438
InChI Key HEOYHMUESMJFDC-RIWXPGAOSA-N
Smiles [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 1 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Harmar et al (1998) International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide. Pharmacol.Rev. 50 265 PMID: 9647867

Laburthe and Couvineau (2002) Molecular pharmacology and structure of VPAC receptors for VIP and PACAP. Regul.Pept. 108 165 PMID: 12220741


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Keywords: VIP (human, rat, mouse, rabbit, canine, porcine), VIP (human, rat, mouse, rabbit, canine, porcine) supplier, Involved, neurotransmission, smooth, muscle, relaxation, Vasoactive, Intestinal, Peptide, Receptors, VPAC, VIP, agonists, (human,, rat,, mouse,, rabbit,, canine,, porcine), 1911, Tocris Bioscience

2 Citations for VIP (human, rat, mouse, rabbit, canine, porcine)

Citations are publications that use Tocris products. Selected citations for VIP (human, rat, mouse, rabbit, canine, porcine) include:

Alcolado et al (2014) Cystic fibrosis transmembrane conductance regulator dysfunction in VIP knockout mice. Am J Physiol Cell Physiol 307 C195 PMID: 24898584

Piet et al (2016) Vasoactive Intestinal Peptide Excites GnRH Neurons in Male and Female Mice. Endocrinology. 157 3621 PMID: 27501185


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Reviews for VIP (human, rat, mouse, rabbit, canine, porcine)

Average Rating: 5 (Based on 1 Review.)

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Good stimulant of mast cells
By Anonymous on 05/30/2018
Assay Type: In Vitro
Species: Human
Cell Line/Tissue: mast cells

Used to stimulate mast cells.


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