Urotensin II-related peptide
Discontinued Product
Urotensin II-related peptide (Cat. No. 2215) has been withdrawn from sale for commercial reasons.
Biological Activity
Potent endogenous agonist for the urotensin-II (UT) receptor. Binds with high affinity and potently activates recombinant rat and human UT receptors (EC50 values are 0.55 and 4.8 nM respectively). Produces hypotensive effects following systemic administration in rats.
Technical Data
| M. Wt | 1017.23 |
| Formula | C49H64N10O10S2 |
| Sequence |
ACFWKYCV (Modifications: Disulfide bridge between 2 - 7) |
| Storage | Desiccate at -20°C |
| CAS Number | 342878-90-4 |
| Smiles | [H]N[C@@H](C)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC1=O)C(=O)N[C@@H](C(C)C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets
References
References are publications that support the biological activity of the product.
Mori and Fujino (2004) Urotensin II-related peptide, the endogenous ligand for the urotensin II receptor in the rat brain. Peptides 25 1815 PMID: 15476951
Chatenet et al (2004) Structure-activity relationships and structural conformation of a novel urotensin II-related peptide. Peptides 25 1819 PMID: 15476952
Sugo et al (2003) Identification of urotensin II-related peptide as the urotensin II-immunoreactive molecule in the rat brain. Biochem.Biophys.Res.Comm. 310 860
View Related Products by Target
View Related Products by Product Action
Keywords: Urotensin II-related peptide, Urotensin II-related peptide supplier, Endogenous, urotensin, II, receptor, agonists, UT, Receptors, Urotensin-II, 2215, Tocris Bioscience
Citations for Urotensin II-related peptide
Citations are publications that use Tocris products.
Currently there are no citations for Urotensin II-related peptide.
Reviews for Urotensin II-related peptide
There are currently no reviews for this product. Be the first to review Urotensin II-related peptide and earn rewards!
Have you used Urotensin II-related peptide?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cardiovascular Research Product Guide
A collection of over 250 products for cardiovascular research, the guide includes research tools for the study of:
- Hypertension
- Thrombosis and Hemostasis
- Atherosclerosis
- Myocardial Infarction
- Ischemia/Reperfusion Injury
- Arrhythmias
- Heart Failure
GPCR Product Listing
A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:
- Rhodopsin-like Receptors
- Secretin-like Receptors
- Glutamate Receptors
- Frizzled Receptors
- GPCR Signaling
Peptide Hormone Receptors Product Listing
A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:
- Anterior Pituitary Regulation
- Blood Pressure Regulation
- Feeding and Appetite Regulation
- Glucose Regulation
- Peptide Hormone Processing
Cardiovascular Poster
Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.
