Tropicamide

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Cat.No. 0909 - Tropicamide | C17H20N2O2 | CAS No. 1508-75-4
Description: Selective M4 muscarinic antagonist
Chemical Name: N-Ethyl-3-hydroxy-2-phenyl-N-(pyridinylmethyl)propanamide
Purity: ≥98% (HPLC)
Datasheet
Citations (1)
Literature

Biological Activity

M4 selective muscarinic receptor antagonist.

Compound Libraries

Tropicamide is also offered as part of the Tocriscreen Plus and Tocriscreen Library of FDA-Approved Compounds. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 284.36
Formula C17H20N2O2
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 1508-75-4
PubChem ID 5593
InChI Key BGDKAVGWHJFAGW-UHFFFAOYSA-N
Smiles CCN(CC1=CC=NC=C1)C(=O)C(CO)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in DMSO

Preparing Stock Solutions

The following data is based on the product molecular weight 284.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.52 mL 17.58 mL 35.17 mL
5 mM 0.7 mL 3.52 mL 7.03 mL
10 mM 0.35 mL 1.76 mL 3.52 mL
50 mM 0.07 mL 0.35 mL 0.7 mL

Molarity Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Hernandez et al (1993) Different muscarinic receptor subtypes mediating the phasic activity and basal tone of pig isolated intravesical ureter. Br.J.Pharmacol. 110 1413 PMID: 7905771

Lazareno et al (1990) Characterisation of muscarinic M4 binding sites in rabbit lung, chicken heart and NG 108-15 cells. Mol.Pharmacol. 38 805 PMID: 2250662


If you know of a relevant reference for Tropicamide, please let us know.

View Related Products by Target

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View all M4 Receptor Antagonists

Keywords: Tropicamide, supplier, Selective, M4, muscarinic, antagonists, Muscarinic, Receptors, Acetylcholine, ACh, M4, Receptors, M4, Receptors, Tocris Bioscience

1 Citation for Tropicamide

Citations are publications that use Tocris products. Selected citations for Tropicamide include:

Sallo et al (2012) The IS/OS junction layer in the natural history of type 2 idiopathic macular telangiectasia. Invest Ophthalmol Vis Sci 53 7889 PMID: 23092925


Do you know of a great paper that uses Tropicamide from Tocris? If so please let us know.

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