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Submit ReviewTropicamide is an M4 selective muscarinic receptor antagonist.
Tropicamide is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen FDA-Approved Drugs. Find out more about compound libraries available from Tocris.
M. Wt | 284.36 |
Formula | C17H20N2O2 |
Storage | Store at RT |
Purity | ≥98% (HPLC) |
CAS Number | 1508-75-4 |
PubChem ID | 5593 |
InChI Key | BGDKAVGWHJFAGW-UHFFFAOYSA-N |
Smiles | CCN(CC1=CC=NC=C1)C(=O)C(CO)C1=CC=CC=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
DMSO | 100 |
The following data is based on the product molecular weight 284.36. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 3.52 mL | 17.58 mL | 35.17 mL |
5 mM | 0.7 mL | 3.52 mL | 7.03 mL |
10 mM | 0.35 mL | 1.76 mL | 3.52 mL |
50 mM | 0.07 mL | 0.35 mL | 0.7 mL |
References are publications that support the biological activity of the product.
Hernandez et al (1993) Different muscarinic receptor subtypes mediating the phasic activity and basal tone of pig isolated intravesical ureter. Br.J.Pharmacol. 110 1413 PMID: 7905771
Lazareno et al (1990) Characterisation of muscarinic M4 binding sites in rabbit lung, chicken heart and NG 108-15 cells. Mol.Pharmacol. 38 805 PMID: 2250662
If you know of a relevant reference for Tropicamide, please let us know.
Keywords: Tropicamide, Tropicamide supplier, Selective, M4, muscarinic, antagonists, Muscarinic, Receptors, Acetylcholine, ACh, 0909, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for Tropicamide include:
Sallo et al (2012) The IS/OS junction layer in the natural history of type 2 idiopathic macular telangiectasia. Invest Ophthalmol Vis Sci 53 7889 PMID: 23092925
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.