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Description: Selective M4 antagonist
Chemical Name: N-Ethyl-3-hydroxy-2-phenyl-N-(pyridinylmethyl)propanamide
Purity: ≥98% (HPLC)
Citations (1)
Literature (2)

Biological Activity for Tropicamide

Tropicamide is an M4 selective muscarinic receptor antagonist.

Compound Libraries for Tropicamide

Tropicamide is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen FDA-Approved Drugs. Find out more about compound libraries available from Tocris.

Technical Data for Tropicamide

M. Wt 284.36
Formula C17H20N2O2
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 1508-75-4
PubChem ID 5593
Smiles CCN(CC1=CC=NC=C1)C(=O)C(CO)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Tropicamide

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 100

Preparing Stock Solutions for Tropicamide

The following data is based on the product molecular weight 284.36. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.52 mL 17.58 mL 35.17 mL
5 mM 0.7 mL 3.52 mL 7.03 mL
10 mM 0.35 mL 1.76 mL 3.52 mL
50 mM 0.07 mL 0.35 mL 0.7 mL

Molarity Calculator

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Dilution Calculator

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Product Datasheets for Tropicamide

Certificate of Analysis / Product Datasheet
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References for Tropicamide

References are publications that support the biological activity of the product.

Hernandez et al (1993) Different muscarinic receptor subtypes mediating the phasic activity and basal tone of pig isolated intravesical ureter. Br.J.Pharmacol. 110 1413 PMID: 7905771

Lazareno et al (1990) Characterisation of muscarinic M4 binding sites in rabbit lung, chicken heart and NG 108-15 cells. Mol.Pharmacol. 38 805 PMID: 2250662

If you know of a relevant reference for Tropicamide, please let us know.

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Keywords: Tropicamide, Tropicamide supplier, Selective, M4, muscarinic, antagonists, Muscarinic, Receptors, Acetylcholine, ACh, 0909, Tocris Bioscience

1 Citation for Tropicamide

Citations are publications that use Tocris products. Selected citations for Tropicamide include:

Sallo et al (2012) The IS/OS junction layer in the natural history of type 2 idiopathic macular telangiectasia. Invest Ophthalmol Vis Sci 53 7889 PMID: 23092925

Do you know of a great paper that uses Tropicamide from Tocris? Please let us know.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Alzheimer's Disease Poster

Alzheimer's Disease Poster

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Learning & Memory Poster

Learning & Memory Poster

Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.