Tris DBA

Pricing Availability Delivery Time Qty
Cat.No. 3416 - Tris DBA | C51H42O3Pd2 | CAS No. 51364-51-3
Description: N-myristoyltransferase-1 inhibitor; antiproliferative
Chemical Name: Tris(dibenzylideneacetone) dipalladium

Biological Activity

N-myristoyltransferase-1 (NMT-1) inhibitor that prevents activation of MAPK, PI 3-K and STAT3 signaling pathways. Exhibits antiproliferative activity against melanoma cells in vitro and in vivo. Also used as a cyclization catalyst.

Technical Data

M. Wt 915.73
Formula C51H42O3Pd2
Storage Store at RT
CAS Number 51364-51-3
PubChem ID 9811564
Smiles [Pd].[Pd].O=C(\C=C\C1=CC=CC=C1)/C=C/C1=CC=CC=C1.O=C(\C=C\C1=CC=CC=C1)/C=C/C1=CC=CC=C1.O=C(\C=C\C1=CC=CC=C1)/C=C/C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 10.07 11

Preparing Stock Solutions

The following data is based on the product molecular weight 915.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.09 mL 5.46 mL 10.92 mL
5 mM 0.22 mL 1.09 mL 2.18 mL
10 mM 0.11 mL 0.55 mL 1.09 mL
50 mM 0.02 mL 0.11 mL 0.22 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Bhandarkar et al (2008) Tris(Dibenzylideneacetone) dipalladium, a N-myristoyltransferase-1 inhibitor, is effective against melanoma growth in vitro and in vivo. Clin.Cancer Res. 14 5743 PMID: 18794083

If you know of a relevant reference for Tris DBA, please let us know.

View Related Products by Product Action

View all Other Transferase Inhibitors

Keywords: Tris DBA, supplier, N-myristoyltransferase-1, inhibitors, inhibits, antiproliferative, Transferases, TrisDBA, Other, Transferases, Post-translational, Modifications, Other, Transferases, Tocris Bioscience

Citations for Tris DBA

Citations are publications that use Tocris products.

Currently there are no citations for Tris DBA. Do you know of a great paper that uses Tris DBA from Tocris? If so please let us know.

Tris DBA Reviews

Average Rating:

(Based on 0 Reviews)

1 Star
2 Star
3 Star
4 Star
5 Star

Have you used Tris DBA?

Submit a review and receive a $25US/€18/£15/$25CAN Amazon gift card if you include an image -$10US/€7/£6/$10CAN Amazon gift card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Literature in this Area

New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Apoptosis
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells