Trimethylserotonin iodide

Discontinued Product

Unfortunately Trimethylserotonin iodide (Cat. No. 0536) has been withdrawn from sale for commercial reasons.
Cat.No. 0536 - Trimethylserotonin iodide | CAS No. 5787-02-0
Description: 5-HT3 agonist.
Chemical Name: 2-(5-Hydroxy-3-indolyl)ethyltrimethylammonium iodide

Biological Activity

5-HT3 agonist. The quaternary analogue of serotonin which does not cross the blood-brain barrier.

Technical Data

M. Wt 346.21
Storage Desiccate at +4°C
CAS Number 5787-02-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 346.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.89 mL 14.44 mL 28.88 mL
5 mM 0.58 mL 2.89 mL 5.78 mL
10 mM 0.29 mL 1.44 mL 2.89 mL
50 mM 0.06 mL 0.29 mL 0.58 mL

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Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service
Safety Datasheet


References are publications that support the products' biological activity.

Richardson et al (1985) Identification of serotonin M-receptor sub-types and their specific blockade by a new class of drugs. Nature 316 126 PMID: 3839291

Glennon et al (1990) Abstr.2nd IUPHAR Satellite meeting on Serotonin. 42 PMID:

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Keywords: Trimethylserotonin iodide, supplier, 5-HT3, Receptors, 5-HT3, Receptors, Tocris Bioscience

Citations for Trimethylserotonin iodide

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

5-HT Receptors

5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.