trans-4-Phenylchalcone oxide

Discontinued Product

Unfortunately trans-4-Phenylchalcone oxide (Cat. No. 0615) has been withdrawn from sale for commercial reasons.
Cat.No. 0615 - trans-4-Phenylchalcone oxide | C21H16O2 | CAS No. 36047-01-5
Description: trans -Styrene oxide hydrolase inhibitor

Biological Activity

Potent and selective inhibitor of trans-styrene oxide hydrolase. IC50 = 64 nM for trans-β-ethylstyrene oxide in mouse liver cytosol.

Technical Data

M. Wt 300.36
Storage Store at RT
CAS Number 36047-01-5
Smiles O=C(C4=CC=CC=C4)C1OC1C(C=C3)=CC=C3C2=CC=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 300.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.33 mL 16.65 mL 33.29 mL
5 mM 0.67 mL 3.33 mL 6.66 mL
10 mM 0.33 mL 1.66 mL 3.33 mL
50 mM 0.07 mL 0.33 mL 0.67 mL

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Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service
Safety Datasheet


References are publications that support the products' biological activity.

Guenthne (1986) Selective inhibition and selective induction of multiple microsomal epoxide hydrolases. Biochem.Pharmacol. 35 839-845 PMID: 3954789

Mullin and Hammock (1982) Chalcone oxides - potent selective inhibitors of cytosolic epoxide hydrolase. Arch.Biochem.Biophys. 216 423 PMID: 7114846

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Keywords: trans-4-Phenylchalcone oxide, supplier, Other, Hydrolases, Other, Hydrolases, Tocris Bioscience

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Literature in this Area

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