Datasheet
Citations (3)
Reviews

Biological Activity

A collection of 80 kinase inhibitors supplied pre-dissolved in DMSO (250 μL 10 mM solution). Comprises a subset of the Tocriscreen Plus (Cat. No. 5840) compound library. Contains compounds covering more than 40 different target kinases including VEGFR, AKT, CDKs, EGFR, p38 MAPK, Src Kinases and TGF-β receptors.

This replaces Tocriscreen Kinase Inhibitor Toolbox (Cat. No. 3514).

Key Format and Product Details

  • 96-well rack with Matrix storage tubes & SepraSeal caps
  • Pre-dissolved in DMSO
  • Many compounds are exclusive to Tocris
  • Full chemical and biological data available
  • Exceptional purity

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectral Viewer

Spectral Viewer

Technical Data

Storage Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References

References are publications that support the biological activity of the product.

Markussen (2018) GSK3 is a negative regulator of the thermogenic program in brown adipocytes. Sci Rep 8 3469 PMID: 29472592

Azad et al (2018) A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis. Nat.Commun. 9 PMID: 29535383

Keywords: Tocriscreen Kinase Inhibitor Toolbox I, Tocriscreen Kinase Inhibitor Toolbox I supplier, , Tocris Bioscience

3 Citations for Tocriscreen Kinase Inhibitor Toolbox I

Citations are publications that use Tocris products. Selected citations for Tocriscreen Kinase Inhibitor Toolbox I include:

Sandilands et al (2015) p70S6K is regulated by focal adhesion kinase and is required for Src-selective autophagy. Cell Signal. 27 1816 PMID: 26071201

Tandon et al (2015) SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest. PLoS One 10 e0119346 PMID: 25747583

Markussen et al (2018) GSK3 is a negative regulator of the thermogenic program in brown adipocytes. Sci.Rep. 8 3469 PMID: 29472592


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