Tocriscreen Kinase Inhibitor Toolbox I
A collection of 80 kinase inhibitors supplied pre-dissolved in DMSO (250 μL 10 mM solution). Comprises a subset of the Tocriscreen Plus (Cat. No. 5840) compound library. Contains compounds covering more than 40 different target kinases including VEGFR, AKT, CDKs, EGFR, p38 MAPK, Src Kinases and TGF-β receptors.
This replaces Tocriscreen Kinase Inhibitor Toolbox (Cat. No. 3514).
Key Format and Product Details
- 96-well rack with Matrix storage tubes & SepraSeal caps
- Pre-dissolved in DMSO
- Many compounds are exclusive to Tocris
- Full chemical and biological data available
- Exceptional purity
Request Compound List
To request a list of the compounds available in the Tocriscreen Kinase Inhibitor Toolbox I please click the request tile below. Compound lists can be provided in Excel or SD format.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
References are publications that support the biological activity of the product.
Markussen (2018) GSK3 is a negative regulator of the thermogenic program in brown adipocytes. Sci Rep 8 3469 PMID: 29472592
Azad et al (2018) A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis. Nat.Commun. 9 PMID: 29535383
If you know of a relevant reference for Tocriscreen Kinase Inhibitor Toolbox I, please let us know.
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Citations for Tocriscreen Kinase Inhibitor Toolbox I
Citations are publications that use Tocris products.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Epigenetics Scientific Review
Written by Susanne Müller-Knapp and Peter J. Brown, this review gives an overview of the development of chemical probes for epigenetic targets, as well as the impact of these tool compounds being made available to the scientific community. In addition, their biological effects are also discussed. Epigenetic compounds available from Tocris are listed.
MAPK Signaling Scientific Review
MAP kinase signaling is integral to the regulation of numerous cellular processes such as proliferation and differentiation, and as a result is an important focus of cancer and immunology research. Updated for 2016, this review discusses the regulation of the MAPK pathway and properties of MAPK cascades. Compounds available from Tocris are listed.
Stem Cells Scientific Review
Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.