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Cat.No. 5390 - Tobramycin | C18H37N5O9 | CAS No. 32986-56-4
Description: Aminoglycoside antibiotic
Chemical Name: O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1-6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1-4)]-2-deoxy-D-streptamine

Biological Activity

Aminoglycoside antibiotic. Exhibits antibacterial activity against strains of Enterobacteriaceae, Pseudomonas and Staphylococcus aureus. Shown to protect lung epithelial cells in vitro against injury from cystic fibrosis bronchial secretions and H2O2.

Technical Data

M. Wt 467.52
Formula C18H37N5O9
Storage Store at +4°C
CAS Number 32986-56-4
PubChem ID 36294
Smiles O[C@H]1C[C@@H](N)[C@](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@@]3([H])O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)([H])O[C@@H]1CN

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
water 46.75 100

Preparing Stock Solutions

The following data is based on the product molecular weight 467.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.14 mL 10.69 mL 21.39 mL
5 mM 0.43 mL 2.14 mL 4.28 mL
10 mM 0.21 mL 1.07 mL 2.14 mL
50 mM 0.04 mL 0.21 mL 0.43 mL

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Dienstag and Neu (1972) In vitro studies of tobramycin, an aminoglycoside antibiotic. Antimicrob.Agents Chemother. 1 41 PMID: 4670427

Cantin and Woods (1993) Protection by antibiotics against myeloperoxidase-dependent cytotoxicity to lung epithelial cells in vitro. PMID: 8380814

If you know of a relevant reference for Tobramycin, please let us know.

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Keywords: Tobramycin, supplier, aminoglycoside, antibiotics, antibacterial, Antibiotics, Tocris Bioscience

Citations for Tobramycin

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Pathways for Tobramycin


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