Theophylline
Biological Activity
Bronchodilator, anti-inflammatory and immunomodulator. Antagonizes adenosine receptors and is a weak non-selective inhibitor of phosphodiesterases (PDEs).
Technical Data
M. Wt | 180.16 |
Formula | C7H8N4O2 |
Storage | Store at RT |
Purity | ≥99% (HPLC) |
CAS Number | 58-55-9 |
PubChem ID | 2153 |
InChI Key | ZFXYFBGIUFBOJW-UHFFFAOYSA-N |
Smiles | O=C1C2=C(N=CN2)N(C)C(N1C)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
water | 4.5 | 25 | |
DMSO | 18.02 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 180.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 5.55 mL | 27.75 mL | 55.51 mL |
5 mM | 1.11 mL | 5.55 mL | 11.1 mL |
10 mM | 0.56 mL | 2.78 mL | 5.55 mL |
50 mM | 0.11 mL | 0.56 mL | 1.11 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Page (1999) Recent advances in our understanding of the use of theophylline in the treatment of asthma. J.Clin.Pharmacol. 39 237 PMID: 10073321
Coward et al (1998) Asthma, adenosine, mast cells and theophylline. Clin.Exp.Allery 28 42 PMID:
Barnes (2003) Theophylline. New perspectives for an old drug. Am.J.Respir.Care Med. 167 813 PMID:
If you know of a relevant reference for Theophylline, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Theophylline, supplier, Phosphodiesterases, inhibitors, inhibits, adenosines, receptor, antagonists, bronchodilator, PDE, Non-Selective, Receptors, Non-selective, Adenosine, Phosphodiesterases, Non-selective, Adenosine, Tocris Bioscience
Citations for Theophylline
Citations are publications that use Tocris products.
Currently there are no citations for Theophylline. Do you know of a great paper that uses Theophylline from Tocris? If so please let us know.
Reviews for Theophylline
There are currently no reviews for this product. Be the first to review Theophylline and earn rewards!
Have you used Theophylline?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and Europe
Submit a Review