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Cat.No. 2795 - Theophylline | C7H8N4O2 | CAS No. 58-55-9
Description: Adenosine receptor antagonist; bronchodilator
Chemical Name: 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
Purity: ≥99% (HPLC)
Literature (4)

Biological Activity for Theophylline

Theophylline is a bronchodilator, anti-inflammatory and immunomodulator. Antagonizes adenosine receptors and is a weak non-selective inhibitor of phosphodiesterases (PDEs).

Technical Data for Theophylline

M. Wt 180.16
Formula C7H8N4O2
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 58-55-9
PubChem ID 2153
Smiles O=C1C2=C(N=CN2)N(C)C(N1C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Theophylline

Solvent Max Conc. mg/mL Max Conc. mM
water 4.5 25
DMSO 18.02 100

Preparing Stock Solutions for Theophylline

The following data is based on the product molecular weight 180.16. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.55 mL 27.75 mL 55.51 mL
5 mM 1.11 mL 5.55 mL 11.1 mL
10 mM 0.56 mL 2.78 mL 5.55 mL
50 mM 0.11 mL 0.56 mL 1.11 mL

Molarity Calculator

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References for Theophylline

References are publications that support the biological activity of the product.

Page (1999) Recent advances in our understanding of the use of theophy. in the treatment of asthma. J.Clin.Pharmacol. 39 237 PMID: 10073321

Coward et al (1998) Asthma, adenosine, mast cells and theophy. Clin.Exp.Allery 28 42

Barnes (2003) Theophylline. New perspectives for an old drug. Am.J.Respir.Care Med. 167 813

If you know of a relevant reference for Theophylline, please let us know.

View Related Products by Product Action

View all Non-selective Adenosine Antagonists

Keywords: Theophylline, Theophylline supplier, Phosphodiesterases, inhibitors, inhibits, adenosines, receptor, antagonists, bronchodilator, PDE, Non-Selective, Receptors, Non-selective, Adenosine, 2795, Tocris Bioscience

Citations for Theophylline

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Currently there are no citations for Theophylline. Do you know of a great paper that uses Theophylline from Tocris? Please let us know.

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