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Submit ReviewBronchodilator, anti-inflammatory and immunomodulator. Antagonizes adenosine receptors and is a weak non-selective inhibitor of phosphodiesterases (PDEs).
M. Wt | 180.16 |
Formula | C7H8N4O2 |
Storage | Store at RT |
Purity | ≥99% (HPLC) |
CAS Number | 58-55-9 |
PubChem ID | 2153 |
InChI Key | ZFXYFBGIUFBOJW-UHFFFAOYSA-N |
Smiles | O=C1C2=C(N=CN2)N(C)C(N1C)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
water | 4.5 | 25 | |
DMSO | 18.02 | 100 |
The following data is based on the product molecular weight 180.16. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 5.55 mL | 27.75 mL | 55.51 mL |
5 mM | 1.11 mL | 5.55 mL | 11.1 mL |
10 mM | 0.56 mL | 2.78 mL | 5.55 mL |
50 mM | 0.11 mL | 0.56 mL | 1.11 mL |
References are publications that support the biological activity of the product.
Page (1999) Recent advances in our understanding of the use of theophy. in the treatment of asthma. J.Clin.Pharmacol. 39 237 PMID: 10073321
Coward et al (1998) Asthma, adenosine, mast cells and theophy. Clin.Exp.Allery 28 42
Barnes (2003) Theophylline. New perspectives for an old drug. Am.J.Respir.Care Med. 167 813
If you know of a relevant reference for Theophylline, please let us know.
Keywords: Theophylline, Theophylline supplier, Phosphodiesterases, inhibitors, inhibits, adenosines, receptor, antagonists, bronchodilator, PDE, Non-Selective, Receptors, Non-selective, Adenosine, 2795, Tocris Bioscience
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